DAVID M. RAPOPORT, M.D.
Osteopathic Medicine at 98 St, New York, NY

5535739, Jul 16, 1996

Jun 7, 1995

8/482866

David M. Rapoport - New York NY
Robert G. Norman - New Windsor NY
Roger A. Gruenke - Overland Park KS

New York University - New York NY
Nellcor Puritan Bennett - Lenexa KS

A61M 1600

12820423

In the treatment of obstructive sleep apnea a method and apparatus are disclosed for optimizing the controlled positive pressure to minimize the flow of air from a flow generator while still ensuring that flow limitation in the patient's airway does not occur. In particular, the invention relates to a breathing device and method of use to adjust a controlled positive pressure to the airway of a patient by detecting flow limitation from analysis of an inspiratory flow waveform. Once the presence of flow limitation has been analyzed, the system determines an action to take for adjustment of the controlled positive pressure. The pressure setting is raised, lowered or maintained depending on whether flow limitation has been detected and on the previous actions taken by the system. The preferred breathing apparatus consists of a flow generator, a flow sensor, an analog to digital converter, a microprocessor, and a pressure controller, a patient supply hose, a nasal fitting, and, optionally, a pressure transducer. Using the method of the present invention, the microprocessor adjusts the air pressure in the patient supply hose when flow limitation is detected in the airway of the patient.

6988994, Jan 24, 2006

Aug 14, 2003

10/642459

David M. Rapoport - New York NY, US
Robert G. Norman - New Windsor NY, US

New York University - New York NY

A61B 5/08, A61M 16/00

600538, 12820423, 12820418, 12820426, 600529

Described are a positive airway pressure system and method for treatment of a sleeping disorder in a patient. The system includes a generator, a sensor and a processing arrangement. The generator supplies airflow and applies a pressure at to an airway of a patient. The sensor measures data corresponding to patient's breathing patterns. The processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of at least one of the following patient's states: (i) a regular breathing state, (ii) a sleep disorder breathing state, (iii) a REM sleep state and (iv) a troubled wakefulness state. The processing arrangement adjusts the applied pressure as a function of the patient's state.

7186221, Mar 6, 2007

Aug 24, 2005

11/210568

David M. Rapoport - New York NY, US
Robert G. Norman - New Windsor NY, US

New York University - New York NY

A61B 5/08, A61M 16/00

600538, 12820423, 12820418, 12820426, 600529

Described are a positive airway pressure system and method for treatment of a sleeping disorder in a patient. The system includes a generator, a sensor and a processing arrangement. The generator supplies airflow and applies a pressure at to an airway of a patient. The sensor measures data corresponding to patient's breathing patterns. The processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of at least one of the following patient's states: (i) a regular breathing state, (ii) a sleep disorder breathing state, (iii) a REM sleep state and (iv) a troubled wakefulness state. The processing arrangement adjusts the applied pressure as a function of the patient's state.

2006007, Apr 6, 2006

Sep 30, 2005

11/240124

Indu Ayappa - New York NY, US
Robert Norman - New Windsor NY, US
David Rapoport - New York NY, US

A61M 16/00, A62B 7/00

128204230, 128204180, 128204210

Described is a system including an air pressure supply arrangement, a sensor and a titration device. The air pressure supply arrangement provides air pressure to a patient's airways. The sensor detects input data corresponding to a patient's breathing patterns of a plurality of breaths. The titration device receives and analyzes the input data to determine existence of breathing disorder and corresponding characteristics. The titration device generates output data for adjusting the air pressure supplied to the patient as a function of an index of abnormal respiratory events included in the input data.

5803066, Sep 8, 1998

Feb 12, 1996

8/598577

David M. Rapoport - New York NY
Robert G. Norman - New Windsor NY

New York University - New York NY

A61M 1600

12820423

In the treatment of obstructive sleep apnea, a method and apparatus are disclosed for detecting obstructive apnea and optimizing the controlled positive pressure to minimize the flow of air from a flow generator while still ensuring that flow limitation in the patient's airway does not occur. In particular, the invention relates to a breathing device and method of use to adjust a controlled positive pressure to the airway of a patient by detecting flow limitation from analysis of an inspiratory flow waveform. Once the presence of flow limitation has been analyzed, the system determines an action to take for adjustment of the controlled positive pressure. The pressure setting is raised, lowered or maintained depending on whether flow limitation has been detected and on the previous actions taken by the system. The preferred breathing apparatus consists of a flow generator, a flow sensor, an analog to digital converter, a microprocessor, and a pressure controller, a patient supply hose, a nasal fitting, and, optionally, a pressure transducer. Using the method of the present invention, the microprocessor adjusts the air pressure in the patient supply hose when flow limitation is detected in the airway of the patient.

4655213, Apr 7, 1987

Oct 6, 1983

6/539723

David M. Rapoport - New York NY
I. Barry Sorkin - New York NY

New York University - NY

A61M 1600

12820525

A nose mask assembly for the treatment of obstructive sleep apnea which is comprised of a nose mask adapted to be sealed over the nose of a patient, an inlet for supplying a continuous positive pressure of air to the mask and a threshold valve to release air from the mask.

2005026, Dec 8, 2005

Jun 4, 2004

10/862067

Robert Norman - New Windsor NY, US
David Rapoport - New York NY, US

A62B007/00, A61M016/00

128204230, 128204180, 128204210

Described is a method and system for automated titration of CPAP. The system may include an air pressure supply providing air pressure to a patient's airways and a sensor detecting input data corresponding to a patient's breathing patterns of a plurality of breaths. The system also includes a titration device which receives and analyzes the input data to determine existence of breathing disorder and corresponding characteristics. The titration device generating output data for adjusting the air pressure supplied to the patient as a function of the characteristics of the breathing disorder.

5335654, Aug 9, 1994

May 7, 1992

7/879578

David M. Rapoport - New York NY

New York University - New York NY

A61M 1600

12820423

In the treatment of obstructive sleep apnea, a CPAP flow generator is employed to direct air to a nasal mask fitted to a patient. The airflow from the generator is monitored, and the flow and/or pressure is increased when the waveform of the airflow exhibits characteristics corresponding to flow limitation. The generator may be controlled to repetitively test for waveform variations, in order to adjust the CPAP flow to the minimum level the does not produce flow limitation.

6165133, Dec 26, 2000

Mar 22, 1999

9/068799

David M. Rapoport - New York NY
Robert G. Norman - New York NY

New York University - New York NY

A61B 508

600529

A pressure sensor is combined with a temperature sensor to monitor a patient's breathing patterns. The combination of sensors enables an analysis of the patient's breathing patterns to be made without the use of a face mask even if the patient breathes through the mouth or draws only very weak breaths. The patient's sleep is therefore less likely to be disrupted by the presence of the monitoring equipment and a more accurate diagnosis of any sleep disorder can be made.