Inventors:
Philip Barr - Oakland CA, US
Philip Pemberton - San Mateo CA, US
Patrick Antonelli - Gainesville FL, US
Gregory Schultz - Gainesville FL, US
David Sundin - Antioch CA, US
International Classification:
A61K039/395, A61K031/56
US Classification:
424/146100, 514/171000, 424/046000
Abstract:
The invention is directed to the treatment of otitis media by administration of protease inhibitors. In some embodiments, the protease inhibitors are alpha one-antitrypsin and/or ilomastat.