Inventors:
Akshay Vaishnaw - Arlington MA, US
Kevin Cooper - Moreland Hills OH, US
Daniel Shrager - Princeton NJ, US
Thomas McCormick - Orange Village OH, US
International Classification:
A61K 39/00, A61K 38/13, A61K 31/525, A61K 31/203, A61K 31/4745
US Classification:
424185100, 514011000, 514251000, 514291000, 514559000, 607086000
Abstract:
Methods for treating or preventing an epidermal or dermal disorder, e.g., psoriasis, using a CD2-binding agent, e.g., an inhibitor of the CD2/LFA-3 interaction (e.g., an LFA-3/IgG fusion polypeptide), in combination with an auxiliary agent, e.g., UVB irradiation, are disclosed.