Peter H Slugg
Medical Practice in Princeton, NJ
License number
New Jersey 25MA06024800
Issued Date
Aug 12, 1993
Expiration Date
Jun 30, 2005
Category
Medical Examiners
Type
Medical Doctor
Address
Address
Princeton, NJ
Personal information
See more information about Peter H Slugg at radaris.comName
Address
Phone
72 Manor Ave, Princeton, NJ 08540
72 Manor Dr, Princeton, NJ 08540
7 Manor Ave, Princeton, NJ 08540
Professional information
Modified-Release Vasopeptidase Inhibitor Formulation, Combinations And Method
US Patent:
2004000, Jan 8, 2004
Filed:
Apr 21, 2003
Appl. No.:
10/419397
Inventors:
Peter Slugg - Princeton NJ, US
Nemichand Jain - West Windsor NJ, US
Rajesh Krishna - West Windsor NJ, US
Robert Jerzewski - Belle Mead NJ, US
Ronald Smith - Yardley PA, US
Jatin Patel - West Windsor NJ, US
Bimal Malhotra - New Brunswick NJ, US
Nemichand Jain - West Windsor NJ, US
Rajesh Krishna - West Windsor NJ, US
Robert Jerzewski - Belle Mead NJ, US
Ronald Smith - Yardley PA, US
Jatin Patel - West Windsor NJ, US
Bimal Malhotra - New Brunswick NJ, US
International Classification:
A61K031/554, A61K009/22
US Classification:
424/468000, 514/211050
Abstract:
A modified-release vasopeptidase inhibitor formulation is provided which is capable of releasing vasopeptidase inhibitor, preferably omapatrilat or gemopatrilat, in a manner to provide therapeutically effective NEP inhibitory activity and therapeutically effective ACE inhibitory activity, in a balanced manner, for a predetermined duration to lower blood pressure and/or treat heart failure. In a preferred formulation, the NEP inhibitory activity and ACE inhibitory activity have balanced release characteristics. Combinations including the above formulation and a diuretic and/or other therapeutic agents and methods for lowering blood pressure employing the above formulation and/or combination and a method for enhancing or balancing NEP inhibitory activity of a vasopeptidase inhibitor are also provided.