Inventors:
Christopher Cannizzaro - Cambridge MA, US
Urs Von Stockar - Lutry, CH
Assignee:
ISMATEC SA, LABORATORIUMSTECHNIK - Glattbrugg
International Classification:
C12Q 1/00, C12M 1/00
US Classification:
422119000, 422050000, 435289100
Abstract:
The invention relates to a device for automated bioreactor sampling connected to a reactor comprising a sampler, at least one tube fluidly connecting said reactor with said sampler and a pump for pumping fluids from said reactor to said sampler and vice versa. Particularly simple and essentially dead volume-free sampling can be achieved by providing means for flushing at least parts of the tube with gas/sterile air between individual sampling steps. The invention furthermore relates to a method of operation of such a device.