DR. ARTHUR ASHMAN, DDS
Dentist at 24 St, New York, NY

4536158, Aug 20, 1985

Sep 30, 1982

6/428750

Paul F. Bruins - Brooklyn NY
Arthur Ashman - New York NY

Medical Biological Sciences, Inc. - New York NY

A61K 608

4332011

A porous implantable oral prosthesis which can be used to replicate and replace any hard tissue portion of the mouth such as bone and teeth is described. The prosthesis comprises sintered polymeric particles coated with a hydrophilic material. The polymeric particles vary in size so as to provide an area of relatively coarse porosity where the prosthesis is intended to interface with bone tissue and relatively fine porosity where it is intended to interface with soft tissue. A process for producing such prosthesis by filling a mold with appropriate molding compounds comprised of polymeric particles and a hydrophilic monomer, sintering the particles and polymerizing the monomer by dielectric heating, removing the sintered material from the cooled mold, and placing the prosthesis in a hot liquid to remove residues is described. An entire tooth, including a nonporous crown may be produced. A process for producing a porous replica of a tooth root suitable for implantation immediately after extraction of a tooth is disclosed.

4547390, Oct 15, 1985

Sep 30, 1982

6/428746

Arthur Ashman - New York NY
Paul F. Bruins - Austin TX

Medical Biological Sciences, Inc. - New York NY

A61K 500, A61F 100, B05D 700

427 2

This invention relates to implantable porous prostheses for use as bone or hard tissue replacements anywhere in the body. The porous implants comprise loose, individual polymeric particles of a specified size, coated with a hydrophilic material and barium sulfate particles. The prostheses are biologically compatible in the body and promote bone and tissue ingrowth and attachment. This invention also relates to a method for producing the novel prosthetic devices disclosed herein.

7004977, Feb 28, 2006

Nov 24, 1999

09/448692

Arthur Ashman - New York NY, US

A Enterprises, Inc. - Westport CT

A61F 2/02

623 2373, 623 1611, 623 1111

A soft tissue implant material is formed from biologically-compatible polymeric particles. The particles may have a diameter of up to about 500 microns and intraparticulate pores sized for ingrowth of soft tissue. The particles may have an inner core of a first biologically-compatible polymeric material and an outer layer generally surrounding the inner core, with the outer layer comprised of a second biologically-compatible polymeric material being hydrophilic and having a composition different from the composition of the first polymeric material. The material may be utilized with collagen or other matrix materials. This material may be used in a method of reforming soft tissues by implanting the material within soft body tissues to modify soft tissue defects such as wrinkles or oral gingival tissue defects and reshape soft tissue, e. g. , for urinary bladder inconvenience.

4244689, Jan 13, 1981

Jun 27, 1978

5/919711

Arthur Ashman - New York NY

A61C 800

433175

Nontoxic polymeric plastic medical implants for endosteal and periosteal applications such as filling bone defects, replacing entire bony parts, and tooth replacement either immediately after extraction or subsequent to healing, and a method of fabricating such implants to produce a porous surface having a predetermined pore size, pore depth, and degree of porosity. The method of fabrication of the porous portion of the implant involves adding sodium chloride crystals or other nontoxic leachable substance of controlled particle size corresponding to the desired pore size to a powdered polymer-liquid monomer mixture in relative amounts corresponding to the desired degree of porosity. After heat polymerization without an initiator, followed by abrasive removal of the resulting surface skin, the salt is leached from the plastic to provide said porosity. To obtain bone ingrowth in the case of intraosseous implantation, the pore size must be 200-400 microns, whereas pore size for soft tissue ingrowth should be 50-150 microns.

2005026, Nov 24, 2005

Jul 29, 2003

10/630549

Arthur Ashman - New York NY, US

A61M037/00

604082000, 606093000, 604190000

An improved assembly of a syringe and a nozzle tip and method of use. The syringe includes nozzle tip having a sleeve portion that fits on the free end of the syringe barrel and a curved nozzle end. The nozzle tip may include a filter screen of preselected mesh size. In use, a preselected amount of marrow blood may be aspirated through the curved aspirating nozzle end and filter screen into the syringe barrel where it mixes with bone regeneration material therein to form a viscous fluid mixture. The nozzle tip is removed from the syringe and the mixture is expelled from the syringe and applied to a surgical site by depressing the syringe plunger.

2002011, Aug 29, 2002

Apr 24, 2002

10/132793

Arthur Ashman - New York NY, US

A61C005/04

433/090000, 604/218000

An improved assembly of a syringe and a nozzle tip and method of use. The syringe includes nozzle tip having a sleeve portion that fits on the free end of the syringe barrel and a curved nozzle end. The nozzle tip may include a filter screen of preselected mesh size. In use, a preselected amount of marrow blood may be aspirated through the curved aspirating nozzle end and filter screen into the syringe barrel where it mixes with bone regeneration material therein to form a viscous fluid mixture. The nozzle tip is removed from the syringe and the mixture is expelled from the syringe and applied to a surgical site by depressing the syringe plunger.

4728570, Mar 1, 1988

Oct 29, 1985

6/792352

Arthur Ashman - New York NY
Itzhak Binderman - Tel Aviv, IL

United States Surgical Corporation - Norwalk CT

A61K 608

428327

An implant material for hard tissue comprising a porous matrix of a mass of biologically-compatible polymeric particles, the particles bonded together to form a unitary prosthetic implant, the prosthetic implant having interstices between the bonded particles forming pores into which bone tissue can grow and having a quantity of calcium hydroxide distributed in the pores of the matrix. Also disclosed is a packing material for forming in vivo prosthetic implants for hard tissue, the packing material comprising a mass of disjoint polymeric particles having an inner core and an outer coating and a quantity of calcium hydroxide distributed in the mass of polymeric particles effective to induce hard tissue growth.

4535485, Aug 20, 1985

Mar 12, 1982

6/357739

Arthur Ashman - New York NY
Paul F. Bruins - Austin TX

Medical Biological Sciences, Inc. - New York NY

A61F 100, A61F 504

623 16

This invention relates to implantable porous prostheses for use as bone or hard tissue replacements anywhere in the body. The porous implants comprise loose, individual polymeric particles of a specified size, coated with a hydrophilic material and barium sulfate particles. The prostheses are biologically compatible in the body and promote bone and tissue ingrowth and attachment. This invention also relates to a method for producing the novel prosthetic devices disclosed herein.