Inventors:
Anthony P. Heaney - Los Angeles CA, US
Hongxiang Hui - Los Angeles CA, US
Assignee:
CEDARS-SINAI MEDICAL CENTER - Los Angeles CA
International Classification:
A61K 51/06, A61P 35/00, A61K 31/713, A61K 31/70, A61K 39/385, A61K 31/51, A61K 101/00, A61K 101/02, A61K 103/00, A61K 103/10, A61K 103/20, A61K 103/30
US Classification:
424 173, 514 44 A, 514 23, 4242361, 514276
Abstract:
The methods and compositions of the invention are based on the preferential utilization of fructose by cancer cells. This invention relates to compositions, methods and kits utilizing fructose and other monosaccharides for the treatment of cancer. This invention also relates to methods and kits for using compositions to mimic or corrupt metabolic pathways of fructose and/or signal transduction pathways related to cancer cells for the treatment of cancer.