Inventors:
Waldemar Priebe - Houston TX, US
Amy Heimberger - Houston TX, US
Izabela Fokt - Houston TX, US
Timothy Madden - Sugarland TX, US
Charles Conrad - Spring TX, US
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM - Austin TX
International Classification:
A61K 38/21, A61K 31/165, A61K 31/706, A61K 31/4164, A61K 45/06, A61K 31/216, A61K 31/44, A61K 31/277
Abstract:
Methods of modulating the INF-induced STAT3 activation in a patient in need-thereof are provided for the treatment of disease. The methods comprise the step of administrating to a patient the combination of a therapeutically effective amount of interferon including INF-α and/or INF-β in combination with a STAT3 inhibitor.