DR. E. EDMUND KIM, M.D.
Radiology at Pressler St, Houston, TX
License number
Texas G0448
Category
Radiology
Type
Nuclear Radiology
Address
Address
1400 Pressler St UNIT 1483, Houston, TX 77030
Phone
(713) 792-3008
(713) 792-4580 (Fax)
(713) 792-4580 (Fax)
Personal information
See more information about E. EDMUND KIM at radaris.comName
Address
Phone
Lewisville, TX
Dallas, TX
Professional information
Ethylenedicysteine (Ec)-Drug Conjugates, Compositions And Methods For Tissue Specific Disease Imaging
US Patent:
6692724, Feb 17, 2004
Filed:
Oct 25, 1999
Appl. No.:
09/434313
Inventors:
David J. Yang - Sugarland TX
Chun W. Liu - Sugarland TX
Dong-Fang Yu - Houston TX
E. Edmond Kim - Houston TX
Chun W. Liu - Sugarland TX
Dong-Fang Yu - Houston TX
E. Edmond Kim - Houston TX
Assignee:
Board of Regents, The University of Texas System - Austin TX
International Classification:
A61K 5100
US Classification:
424 149, 424 111, 424 165, 424 169, 534 14
Abstract:
The invention provides, in a general sense, a new labeling strategy employing Tc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to Tc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.
Conjugates For Dual Imaging And Radiochemotherapy: Composition, Manufacturing, And Applications
US Patent:
2006018, Aug 17, 2006
Filed:
Jan 5, 2006
Appl. No.:
11/326117
Inventors:
David Yang - Sugar Land TX, US
Dongfang Yu - Houston TX, US
Mithu Chanda - Houston TX, US
Ali Azhdarinia - Houston TX, US
Changsok Oh - Houston TX, US
E. Kim - Houston TX, US
Dongfang Yu - Houston TX, US
Mithu Chanda - Houston TX, US
Ali Azhdarinia - Houston TX, US
Changsok Oh - Houston TX, US
E. Kim - Houston TX, US
International Classification:
A61K 49/10, C08B 37/00, A61B 10/00
US Classification:
424009364, 424009500, 424009600, 536053000, 534016000
Abstract:
Compositions and methods for dual imaging and for dual chemotherapy and radiotherapy are disclosed. More particularly, the invention concerns compounds comprising the structure X-Y-X, wherein Y comprises two or more carbohydrate residues covalently attached to one another, Xand Xare diagnostic or therapeutic moieties covalently attached to Y, provided that when Y does not comprise a glucosamine residue, Xand Xare diagnostic moieties. The present invention also concerns methods of synthesis of these compounds, application of such compounds for dual imaging and treatment of hyperproliferative disease, and kits for preparing a radiolabeled therapeutic or diagnostic compound.
Image-Guided Therapy Of Myocardial Disease: Composition, Manufacturing And Applications
US Patent:
2013030, Nov 14, 2013
Filed:
Apr 17, 2013
Appl. No.:
13/864986
Inventors:
Saady KOHANIM - Sugar Land TX, US
Dongfang YU - Houston TX, US
Richard MENDEZ - Houston TX, US
E. Edmund KIM - Houston TX, US
Dongfang YU - Houston TX, US
Richard MENDEZ - Houston TX, US
E. Edmund KIM - Houston TX, US
Assignee:
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM - Austin TX
International Classification:
A61K 51/04, C07F 13/00
US Classification:
424 165, 534 14, 564167
Abstract:
Compositions and methods for imaging and for chemotherapy and radiotherapy are disclosed. More particularly, the invention concerns agents comprising a targeting moeity comprising a beta-adrenergic receptor targeting compound conjugated or embedded with ethylenediamine. The present invention also concerns methods of application of such agents for imaging and treatment of cardiovascular diseases, and kits for preparing a radiolabeled therapeutic or diagnostic agent.
Ethylenedicysteine (Ec)-Drug Conjugates Compositions And Methods For Tissue Specific Disease Imaging
US Patent:
7582281, Sep 1, 2009
Filed:
Jan 25, 2007
Appl. No.:
11/627299
Inventors:
David J. Yang - Sugarland TX, US
Chun W. Liu - Sugarland TX, US
Dong-Fang Yu - Houston TX, US
E. Edmund Kim - Houston TX, US
Chun W. Liu - Sugarland TX, US
Dong-Fang Yu - Houston TX, US
E. Edmund Kim - Houston TX, US
Assignee:
Board of Regents, The University of Texas System - Austin TX
International Classification:
A61K 51/00, A61M 36/14
US Classification:
424 91, 424 111, 424 149, 424 165, 424 169, 424 173, 424 94
Abstract:
The invention provides, in a general sense, a new labeling strategy employing Tc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to Tc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.
Bisaminoethanethiol-Targeting Ligand Conjugates And Compositions
US Patent:
8236279, Aug 7, 2012
Filed:
Sep 21, 2009
Appl. No.:
12/563724
Inventors:
David J. Yang - Sugarland TX, US
Chun W. Liu - Sugarland TX, US
Dong-Fang Yu - Houston TX, US
E. Edmund Kim - Houston TX, US
Chun W. Liu - Sugarland TX, US
Dong-Fang Yu - Houston TX, US
E. Edmund Kim - Houston TX, US
Assignee:
Board of Regents, The University of Texas System - Austin TX
International Classification:
A61K 51/00, A61M 36/14
US Classification:
424 165, 424 111, 424 153, 424 173
Abstract:
The invention provides, in a general sense, a new labeling strategy employing Tc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to Tc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.
Ethylenedicysteine (Ec)-Drug Conjugates, Compositions And Methods For Tissue Specific Disease Imaging
US Patent:
7229604, Jun 12, 2007
Filed:
Sep 26, 2003
Appl. No.:
10/672142
Inventors:
David J. Yang - Sugarland TX, US
Chun W. Liu - Sugarland TX, US
Dong-Fang Yu - Houston TX, US
E. Edmund Kim - Houston TX, US
Chun W. Liu - Sugarland TX, US
Dong-Fang Yu - Houston TX, US
E. Edmund Kim - Houston TX, US
Assignee:
Board of Regents, The University of Texas System - Austin TX
International Classification:
A61K 49/00
US Classification:
424 91, 424 111, 424 165, 424 149, 424 169
Abstract:
The invention provides, in a general sense, a new labeling strategy employing Tc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to Tc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.
Image-Guided Therapy Of Myocardial Disease: Composition, Manufacturing And Applications
US Patent:
8440168, May 14, 2013
Filed:
Dec 19, 2008
Appl. No.:
12/340338
Inventors:
David J. Yang - Sugar Land TX, US
Saady Kohanim - Sugar Land TX, US
Dong-Fang Yu - Houston TX, US
Richard Mendez - Houston TX, US
E. Edmund Kim - Houston TX, US
Saady Kohanim - Sugar Land TX, US
Dong-Fang Yu - Houston TX, US
Richard Mendez - Houston TX, US
E. Edmund Kim - Houston TX, US
Assignee:
The Board of Regents of the University of Texas System - Austin TX
International Classification:
A61K 51/04, A61K 49/00
US Classification:
424 165, 424 936, 424 942, 424 95, 424 945
Abstract:
Compositions and methods for imaging and for chemotherapy and radiotherapy are disclosed. More particularly, the invention concerns agents comprising a targeting moeity comprising a beta-adrenergic receptor targeting compound conjugated or embedded with ethylenediamine. The present invention also concerns methods of application of such agents for imaging and treatment of cardiovascular diseases, and kits for preparing a radiolabeled therapeutic or diagnostic agent.
Ethylenedicysteine (Ec)-Drug Conjugates, Compositions And Methods For Tissue Specific Disease Imaging
US Patent:
7223380, May 29, 2007
Filed:
Sep 26, 2003
Appl. No.:
10/672763
Inventors:
David J. Yang - Sugarland TX, US
Chun W. Liu - Sugarland TX, US
Dong-Fang Yu - Houston TX, US
E. Edmund Kim - Houston TX, US
Chun W. Liu - Sugarland TX, US
Dong-Fang Yu - Houston TX, US
E. Edmund Kim - Houston TX, US
Assignee:
Board of Regents, The University of Texas System - Austin TX
International Classification:
A61K 49/04
US Classification:
424 94, 424 111, 424 165, 424 169, 424 91
Abstract:
The invention provides, in a general sense, a new labeling strategy employing Tc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to Tc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.
Local Regional Chemotherapy And Radiotherapy Using In Situ Hydrogel
US Patent:
2005020, Sep 22, 2005
Filed:
Jan 14, 2005
Appl. No.:
11/036580
Inventors:
David Yang - Sugar Land TX, US
Dong-Fang Yu - Houston TX, US
Ali Azhdarinia - Houston TX, US
Tommy Lee - Spring TX, US
E. Kim - Houston TX, US
Dong-Fang Yu - Houston TX, US
Ali Azhdarinia - Houston TX, US
Tommy Lee - Spring TX, US
E. Kim - Houston TX, US
International Classification:
A61K009/14, A61M031/00
US Classification:
424486000, 604500000
Abstract:
Methods regarding local regional treatment in situ for an individual, such as of a tumor, are provided herein. A hydrogel composition is generated in situ in the tumor by administering a polymer, such as a polysaccharide or a polyamino acid, with a therapeutic agent, such as a radionuclide or a drug, and administering a cross-linking agent. The hydrogel/therapeutic agent composition is retained in the tumor for safe and efficient tumor therapy. Alternatively, a hydrogel composition is generated in situ in an artery which nourishes a tumor to occlude the artery.
Ethylenedicysteine (Ec)-Drug Conjugates, Compositions And Methods For Tissue Specific Disease Imaging
US Patent:
7067111, Jun 27, 2006
Filed:
Jun 21, 2000
Appl. No.:
09/599152
Inventors:
David J. Yang - Sugarland TX, US
Chun W. Liu - Sugarland TX, US
Dong-Fang Yu - Houston TX, US
E. Edmund Kim - Houston TX, US
Chun W. Liu - Sugarland TX, US
Dong-Fang Yu - Houston TX, US
E. Edmund Kim - Houston TX, US
Assignee:
Board of Regents, University of Texas System - Austin TX
International Classification:
A61K 49/00
US Classification:
424 91, 424 111, 424 165, 424 149, 424 169
Abstract:
The invention provides, in a general sense, a new labeling strategy employing Tc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to Tc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.