Inventors:
James Crapo - Englewood CO, US
Brian Day - Englewood CO, US
Ines Batinic-Haberle - Durham NC, US
Richard Gammans - Research Triangle Park NC, US
Zeljko Vujaskovic - Durham NC, US
International Classification:
A61K031/555
Abstract:
The present invention relates, in general, to cancer therapy, and, in particular, to a method of preventing or treating cancer using low molecular weight antioxidants (e.g., mimetics of superoxide dismutase (SOD)) as the active agent or as a chemo- and/or radio-protectant. The invention also relates to compounds and compositions suitable for use in such a method.