DR. ZEA BOROK, M.D.
Osteopathic Medicine at San Pablo St, Los Angeles, CA
License number
California A47911
Category
Osteopathic Medicine
Type
Pulmonary Disease
License number
California A47911
Category
Osteopathic Medicine
Type
Critical Care Medicine
Address
Address
1520 San Pablo St SUITE 1000, Los Angeles, CA 90033
Phone
(323) 226-7923
(323) 226-2738 (Fax)
(323) 442-5100
(323) 226-2738 (Fax)
(323) 442-5100
Personal information
See more information about ZEA BOROK at radaris.comName
Address
Phone
116 N Lucerne Blvd, Los Angeles, CA 90004
725 N Ogden Dr, Los Angeles, CA 90046
116 Lucerne Ave, Los Angeles, CA 90004
Organization information
See more information about ZEA BOROK at bizstanding.comZea Borok MD
1520 San Pablo St, Los Angeles, CA 90033
Industry:
Internist
Phone:
(323) 226-7923 (Phone)
Zea Borok
Zea Borok MD
1200 N State St, Los Angeles, CA 90089
Categories:
Pulmonary & Respiratory Physicians & Surgeons
Phone:
(323) 226-7923 (Phone)
Professional information
Zea Borok, Los Angeles CA
Specialties:
Internal Medicine, Critical Care Medicine, Pulmonary Disease, General Practice, Radiology
Work:
USC Internal Medicine/USC Care Medical Group
1520 San Pablo St, Los Angeles, CA 90033 Los Angeles County + University of Southern California Medical Center
1200 N State St, Los Angeles, CA 90033 Usc Internal Medicine
1355 San Pablo St, Los Angeles, CA 90033
1520 San Pablo St, Los Angeles, CA 90033 Los Angeles County + University of Southern California Medical Center
1200 N State St, Los Angeles, CA 90033 Usc Internal Medicine
1355 San Pablo St, Los Angeles, CA 90033
Education:
University Of Cape Town (1979)
Dr. Zea Borok, Los Angeles CA - MD (Doctor of Medicine)
Specialties:
Critical Care Medicine, Pulmonology
Address:
USC Healthcare Internal Medcn
1520 San Pablo St SUITE 1000, Los Angeles 90033
(323) 442-5100 (Phone)
1520 San Pablo St SUITE 1000, Los Angeles 90033
(323) 442-5100 (Phone)
Certifications:
Critical Care Medicine, 2000, Internal Medicine, 1985, Pulmonary Disease, 2000
Awards:
Healthgrades Honor Roll
Languages:
English, Hebrew
Hospitals:
USC Healthcare Internal Medcn
1520 San Pablo St SUITE 1000, Los Angeles 90033
USC Norris Comprehensive Cancer Center
1441 Eastlake Ave, Los Angeles 90089
1520 San Pablo St SUITE 1000, Los Angeles 90033
USC Norris Comprehensive Cancer Center
1441 Eastlake Ave, Los Angeles 90089
Education:
Medical School
University Of Cape Town, Faculty Of Health Sciences
Graduated: 1979
Groote Schuur Hospital
Graduated: 1980
Fell University Pittsburgh
Graduated: 1987
Montefiore Hospital
Graduated: 1985
National Institute Of Health
Graduated: 1990
University Of Cape Town, Faculty Of Health Sciences
Graduated: 1979
Groote Schuur Hospital
Graduated: 1980
Fell University Pittsburgh
Graduated: 1987
Montefiore Hospital
Graduated: 1985
National Institute Of Health
Graduated: 1990
Zea Borok, Los Angeles CA
Specialties:
Internist
Address:
1520 San Pablo St, Los Angeles, CA 90033
Education:
University of Cape Town, Faculty of Health Sciences - Doctor of Medicine
National Institutes of Health-Clinical Center - Fellowship - Pulmonary Disease (Internal Medicine)
UPMC Montefiore - Residency - Internal Medicine
National Institutes of Health-Clinical Center - Fellowship - Pulmonary Disease (Internal Medicine)
UPMC Montefiore - Residency - Internal Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine, American Board of Internal Medicine Sub-certificate in Critical Care Medicine (Internal Medicine)
Lentivirus Vectors For Gene Transfer To Alveolar Epithelial Cells
US Patent:
7601345, Oct 13, 2009
Filed:
Mar 9, 2007
Appl. No.:
11/716173
Inventors:
Zea Borok - Los Angeles CA, US
Nori Kasahara - Los Angeles CA, US
Edward Crandall - Los Angeles CA, US
Nori Kasahara - Los Angeles CA, US
Edward Crandall - Los Angeles CA, US
Assignee:
University of Southern California - Los Angeles CA
International Classification:
A01N 63/00, A61K 48/00, C12N 15/00, C12N 15/63
US Classification:
424 9321, 424 932, 424 936, 4353201, 435455
Abstract:
The present invention demonstrates that VSV-G-pseudotyped lentivirus vectors efficiently transduce AEC in primary culture and in vivo with transduction favored by virus application from the apical side. Transduction efficiency in AEC increased with increasing MOI and greatly exceeded that achieved with a similarly pseudotyped MLV retrovirus vector. The present invention also demonstrates the successful in vivo transfer of genes through lentivirus vector transduction. Mammals injected with lentivirus vector via the trachea expressed the reporter protein in alveolar epithelial cells within 48 to 72 hours after infection.
Lentivirus Vectors For Gene Transfer To Alveolar Epithelial Cells
US Patent:
2002018, Dec 5, 2002
Filed:
Apr 9, 2002
Appl. No.:
10/119499
Inventors:
Zea Borok - Los Angeles CA, US
Nori Kasahara - Los Angeles CA, US
Edward Crandall - Los Angeles CA, US
Nori Kasahara - Los Angeles CA, US
Edward Crandall - Los Angeles CA, US
Assignee:
University of Southern California - Los Angeles CA
International Classification:
C12N015/867, C12N007/00
US Classification:
435/456000, 435/235100, 435/320100
Abstract:
The present invention demonstrates that VSV-G-pseudotyped lentivirus vectors efficiently transduce AEC in primary culture and in vivo with transduction favored by virus application from the apical side. Transduction efficiency in AEC increased with increasing MOI and greatly exceeded that achieved with a similarly pseudotyped MLV retrovirus vector. The present invention also demonstrates the successful in vivo transfer of genes through lentivirus vector transduction. Mammals injected with lentivirus vector via the trachea expressed the reporter protein in alveolar epithelial cells within 48 to 72 hours after infection.