Inventors:
M. Daniel Raftery - West Lafayette IN, US
Danijel Djukovic - Indianapolis IN, US
Zane Hammoud - Northville MI, US
Assignee:
Purdue Research Foundation - West Lafayette IN
International Classification:
G01N 33/574, C07H 19/067, G01N 21/00, C07H 19/167
US Classification:
436501, 536 276, 536 2781, 536 285, 536 2853, 2524081
Abstract:
Results of studies of nucleosides in biofluid specimens from patients with esophageal adenocarcinoma and related disorders have identified five biomarkers of the conditions: 1-methyladenosine, N,N-dimethylguanosine, N-methylguanosine, cytidine and uridine. In certain embodiments, methods of measuring these biomarkers and kits for measuring these biomarkers are provided.