Inventors:
Thomas Giordano - Ann Arbor MI, US
Ronald Koenig - Ann Arbor MI, US
Rork Kuick - Dexter MI, US
Samir Hanish - Mercer Island WI, US
Dafydd G. Thomas - Fenton MI, US
Yuri Nikiforov - Pittsburgh PA, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
The University of Cincinnati - Cincinnati OH
International Classification:
C12Q 1/68, G01N 33/53
US Classification:
435 612, 435 6, 435 614, 435 71
Abstract:
The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with thyroid cancers. Genes identified as cancer markers using the methods of the present invention find use in the diagnosis and characterization of thyroid cancer. In addition, the genes provide targets for cancer drug screens and therapeutic applications.