YUN WU, M.D., PHD
Medical Practice at Holcombe Blvd, Houston, TX
License number
Texas L6220
Category
Medical Practice
Type
Anatomic Pathology & Clinical Pathology
Address
Address
1515 Holcombe Blvd, Houston, TX 77030
Phone
(713) 792-6161
(713) 792-2991
(713) 792-2991
Personal information
See more information about YUN WU at radaris.comName
Address
Phone
6106 Mettler Ln, Richmond, TX 77469
5000 Maple St, Bellaire, TX 77401
3402 Appleton Dr, Pearland, TX 77584
4432 Darsey St, Bellaire, TX 77401
9224 Beechnut St, Houston, TX 77036
Professional information
Bcr-Abl Directed Compositions And Uses For Inhibiting Philadelphia Chromesome Stimulated Cell Growth
US Patent:
6537804, Mar 25, 2003
Filed:
Jun 21, 1999
Appl. No.:
09/101059
Inventors:
Ralph B. Arlinghaus - Bellaire TX
Jiaxin Liu - Bellaire TX
Dai Lu - Pearland TX
Yun Wu - Houston TX
Jiaxin Liu - Bellaire TX
Dai Lu - Pearland TX
Yun Wu - Houston TX
Assignee:
Board of Regents, The University of Texas Systems - Austin TX
International Classification:
C07H 2104
US Classification:
4353201, 536 231, 530300, 530350, 435 6
Abstract:
The present invention provides methods for detecting and quantitating BCR-ABL gene products and other abnormal ABL gene products of Ph -positive leukemic cells. The invention further provides methods for determining the relative number of leukemic cells compared with normal ABL cells to assess the tumor burden of a patient. In another aspect, the methods of the present invention can be used to determine a specific phase of leukemia, particularly chronic-phase CML.
Bcr-Abl Directed Compositions And Uses For Inhibiting Philadelphia Chromosome Stimulated Cell Growth
US Patent:
2004002, Feb 5, 2004
Filed:
Mar 25, 2003
Appl. No.:
10/397062
Inventors:
Ralph Arlinghaus - Bellaire TX, US
Jiaxin Liu - Bellaire TX, US
Dai Lu - Pearland TX, US
Yun Wu - Houston TX, US
Jiaxin Liu - Bellaire TX, US
Dai Lu - Pearland TX, US
Yun Wu - Houston TX, US
International Classification:
A61K048/00, C12Q001/68, C07H021/04, C12P021/02, C12N005/08, C07K014/705
US Classification:
424/093210, 435/006000, 435/069100, 435/320100, 435/372000, 530/350000, 536/023500
Abstract:
Compositions comprising or encoding one or more peptides that inhibit the Bcr—Abl oncoprotein and that bind to molecules involved in Bcr—Abl function are disclosed. The peptides and polypeptides inhibit the growth of, and induce cell death of, Philadelphia chromosome-positive leukemia cells expressing the Bcr—Abl oncoprotein. Methods for treating leukemias (e.g., CML, ALL and AML), including autologous bone marrow transplant therapy, using the peptide and polypeptide compositions of the invention are also provided.