YUN WANG
Social Work at South St, Boston, MA
License number
Massachusetts 10331
Category
Social Work
Type
Clinical
Address
Address
145 South St SOUTH, Boston, MA 02111
Phone
(617) 318-3233
Professional information
Research Assistant At Harvard University
Position:
research assistant at Harvard University
Location:
Greater Boston Area
Industry:
Higher Education
Work:
Harvard University
-
research assistant
Reversible Inhibition Of Pyramidal Gap Junction Activity
US Patent:
7704946, Apr 27, 2010
Filed:
May 3, 2007
Appl. No.:
11/800113
Inventors:
Yun Wang - Chestnut Hill MA, US
Assignee:
Caritas St. Elizabeth's Medical Center - Boston MA
International Classification:
A61K 38/17, A61K 38/04
US Classification:
514 2, 435 4
Abstract:
The present invention relates to a novel method of inhibiting gap junction-mediated signaling in pyramid cells. Pyramidal gap junctions are quickly and reversibly inhibited by beta-amyloid or biologically active fragments thereof. The present invention also relates to the use of beta-amyloid as an anticonvulsant for the treatment of epilepsy and other pathological hypersynchrony conditions in humans and non-human animals.