Yun Shan Wang
Psychologist in Boston, MA
License number
Massachusetts 10331
Issued Date
Mar 8, 2016
Expiration Date
Jun 30, 2018
Type
Psychologist
Address
Address
Boston, MA 02111
Professional information
Research Assistant At Harvard University
Position:
research assistant at Harvard University
Location:
Greater Boston Area
Industry:
Higher Education
Work:
Harvard University
-
research assistant
Reversible Inhibition Of Pyramidal Gap Junction Activity
US Patent:
7704946, Apr 27, 2010
Filed:
May 3, 2007
Appl. No.:
11/800113
Inventors:
Yun Wang - Chestnut Hill MA, US
Assignee:
Caritas St. Elizabeth's Medical Center - Boston MA
International Classification:
A61K 38/17, A61K 38/04
US Classification:
514 2, 435 4
Abstract:
The present invention relates to a novel method of inhibiting gap junction-mediated signaling in pyramid cells. Pyramidal gap junctions are quickly and reversibly inhibited by beta-amyloid or biologically active fragments thereof. The present invention also relates to the use of beta-amyloid as an anticonvulsant for the treatment of epilepsy and other pathological hypersynchrony conditions in humans and non-human animals.