Inventors:
Guoqiang Wang - Belmont MA, US
Ly Tam Phan - Quincy MA, US
Yat Sun Or - Watertown MA, US
Yao-Ling Qiu - Andover MA, US
Deqiang Niu - Lexington MA, US
Yulin Peng - Waltham MA, US
Marina Busuyek - Center Valley PA, US
Yanchun Wang - Newton MA, US
Suanne Nakajima - Winchester MA, US
International Classification:
A61K 31/7048, C07H 17/08
Abstract:
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes processes by which to make the compounds of the present invention.