YUAN QIAO, M.D.
Student, Health Care at Belvedere Ave, Baltimore, MD
License number
Maryland P31347
Category
Student, Health Care
Type
Student in an Organized Health Care Education/Training Program
Address
Address
2401 W Belvedere Ave, Baltimore, MD 21215
Phone
(410) 601-9386
Professional information
See more information about YUAN QIAO at trustoria.com
Research Fellow At Ludwig Center For Cancer Genetics And Therapeutics At Johns Hopkins
Research Fellow At Ludwig Center For Cancer Genetics And Therapeutics At Johns Hopkins
Location:
Baltimore, Maryland Area
Industry:
Research
Detecting And Treating Solid Tumors Through Selective Disruption Of Tumor Vasculature
Detecting And Treating Solid Tumors Through Selective Disruption Of Tumor Vasculature
US Patent:
2013032, Dec 5, 2013
Filed:
Oct 20, 2011
Appl. No.:
13/880608
Inventors:
Bert Vogelstein - Baltimore MD, US
Yuan Qiao - Baltimore MD, US
Xin Huang - Baltimore MD, US
Kenneth Kinzler - Baltimore MD, US
Shibin Zhou - Owings Mills MD, US
Luis Diaz - Ellicott City MD, US
Yuan Qiao - Baltimore MD, US
Xin Huang - Baltimore MD, US
Kenneth Kinzler - Baltimore MD, US
Shibin Zhou - Owings Mills MD, US
Luis Diaz - Ellicott City MD, US
Assignee:
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
International Classification:
A61K 51/10
US Classification:
424 149, 424400, 424450, 424 111
Abstract:
Several agents capable of inducing vascular responses akin to those observed in inflammatory processes enhance the accumulation of nanoparticles in tumors. Exemplary vascular-active agents include a bacterium, a pro-inflammatory cytokine, and microtubule-destabilizing drugs. Such agents can increase the tumor to blood ratio of radioactivity by more than 20-fold compared to nanoparticles alone. Moreover, vascular-active agents dramatically improved the therapeutic effect of nanoparticles containing radioactive isotopes or chemotherapeutic agents.