YUAN QIAO, M.D.
Student, Health Care at Belvedere Ave, Baltimore, MD
License number
Maryland P31347
Category
Student, Health Care
Type
Student in an Organized Health Care Education/Training Program
Address
Address
2401 W Belvedere Ave, Baltimore, MD 21215
Phone
(410) 601-9386
Professional information
Research Fellow At Ludwig Center For Cancer Genetics And Therapeutics At Johns Hopkins
Location:
Baltimore, Maryland Area
Industry:
Research
Detecting And Treating Solid Tumors Through Selective Disruption Of Tumor Vasculature
US Patent:
2013032, Dec 5, 2013
Filed:
Oct 20, 2011
Appl. No.:
13/880608
Inventors:
Bert Vogelstein - Baltimore MD, US
Yuan Qiao - Baltimore MD, US
Xin Huang - Baltimore MD, US
Kenneth Kinzler - Baltimore MD, US
Shibin Zhou - Owings Mills MD, US
Luis Diaz - Ellicott City MD, US
Yuan Qiao - Baltimore MD, US
Xin Huang - Baltimore MD, US
Kenneth Kinzler - Baltimore MD, US
Shibin Zhou - Owings Mills MD, US
Luis Diaz - Ellicott City MD, US
Assignee:
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
International Classification:
A61K 51/10
US Classification:
424 149, 424400, 424450, 424 111
Abstract:
Several agents capable of inducing vascular responses akin to those observed in inflammatory processes enhance the accumulation of nanoparticles in tumors. Exemplary vascular-active agents include a bacterium, a pro-inflammatory cytokine, and microtubule-destabilizing drugs. Such agents can increase the tumor to blood ratio of radioactivity by more than 20-fold compared to nanoparticles alone. Moreover, vascular-active agents dramatically improved the therapeutic effect of nanoparticles containing radioactive isotopes or chemotherapeutic agents.