YOUNG KWON, DDS
Dentist at University Ave, Ann Arbor, MI

License number
Michigan 2901022272
Category
Dentist
Type
General Practice
Address
Address
1011 N University Ave, Ann Arbor, MI 48109
Phone
(734) 764-1542
(734) 615-1415 (Fax)

Professional information

See more information about YOUNG KWON at trustoria.com
Young Kwon Photo 1
Anti-Cocaine Compositions And Treatment

Anti-Cocaine Compositions And Treatment

US Patent:
2013013, May 30, 2013
Filed:
Nov 14, 2012
Appl. No.:
13/676324
Inventors:
The Trustees of Columbia University in the City of - New York NY, US
James H. Woods - Ann Arbor MI, US
Roger Sunahara - Ann Arbor MI, US
Diwahar L. Narasimhan - Ann Arbor MI, US
Joanne MacDonald - New York NY, US
Victor Yang - Ann Arbor MI, US
Mei-Chuan Holden Ko - Ann Arbor MI, US
John J. Tesmer - Ann Arbor MI, US
Tien-Yi Lee - Ann Arbor MI, US
Young Min Kwon - Ann Arbor MI, US
Daquan Gao - Louisville KY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C12N 9/18
US Classification:
424 946, 536 232, 435197
Abstract:
Embodiments of the invention disclosed herein generally relate to anti-cocaine therapeutics. Specifically, some embodiments of the invention relate to highly efficient, thermostable, and long-lasting cocaine esterase (CocE) mutants that can protect against the toxic and reinforcing effects of cocaine in subjects. Provided herein are mutant CocE polypeptides displaying thermostable esterase activity. Also provided are methods of treating cocaine-induced conditions in a subject in need via administration of mutant CocE as well as methods for high-throughput screening of candidate esterase polypeptides.


Young Kwon Photo 2
Anti-Cocaine Compositions And Treatment

Anti-Cocaine Compositions And Treatment

US Patent:
8318156, Nov 27, 2012
Filed:
Jul 10, 2007
Appl. No.:
12/373510
Inventors:
Donald W Landry - New York NY, US
Joanne MacDonald - New York NY, US
Daquan Gao - Louisville KY, US
James H. Woods - Ann Arbor MI, US
Roger K. Sunahara - Ann Arbor MI, US
Diwahar L. Narasimhan - Ann Arbor MI, US
Victor Yang - Ann Arbor MI, US
Mei-Chuan Holden Ko - Ann Arbor MI, US
John J. Tesmer - Ann Arbor MI, US
Tien-Yi Lee - Ann Arbor MI, US
Young Min Kwon - Ann Arbor MI, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
The Regents of the University of Michigan - Ann Arbor MI
University of Kentucky Research Foundation - Lexington KY
International Classification:
A61K 38/46, A61K 38/43, C12N 9/16, C12N 9/14, C12P 21/06, C12P 19/34, C07H 21/04
US Classification:
424 946, 424 941, 435196, 435195, 435 691, 435 911, 536 231, 536 232, 530350
Abstract:
Embodiments of the invention disclosed herein generally relate to anti-cocaine therapeutics. Specifically, some embodiments of the invention relate to highly efficient, thermostable, and long-lasting cocaine esterase (CocE) mutants that can protect against the toxic and reinforcing effects of cocaine in subjects. Provided herein are mutant CocE polypeptides displaying thermostable esterase activity. Also provided are methods of treating cocaine-induced conditions in a subject in need via administration of mutant CocE as well as methods for high-throughput screening of candidate esterase polypeptides.


Young Kwon Photo 3
Erythrocyte-Encapsulated L-Asparaginase For Enhanced Acute Lymphoblastic Leukemia Therapy

Erythrocyte-Encapsulated L-Asparaginase For Enhanced Acute Lymphoblastic Leukemia Therapy

US Patent:
2010028, Nov 11, 2010
Filed:
Dec 22, 2008
Appl. No.:
12/318112
Inventors:
Victor C. Yang - Ann Arbor MI, US
Young M. Kwon - Ann Arbor MI, US
Hee S. Chung - Ann Arbor MI, US
Arthur J. Yang - York PA, US
International Classification:
A61K 35/18, A61P 35/00, A61P 35/02, C12N 9/82, C12N 9/96
US Classification:
424 9373, 435229, 435188
Abstract:
Compositions for transporting L-asparaginase across the cellular membrane of erythrocytes, comprising a low molecular weight protamine peptide. Process of preparation of compositions comprising conjugates of L-asparaginase and a low molecular weight protamine peptide. Method of treatment comprising administration of adapted L-asparaginase is also described.