Inventors:
Young K. Chen - San Diego CA, US
Eric Wang Co - San Diego CA, US
Prasuna Guntupalli - San Diego CA, US
John David Lawson - Carlsbad CA, US
Wolfgang Reinhard Ludwig Notz - San Diego CA, US
Jeffrey A. Stafford - San Diego CA, US
Huong-Thu Ton-Nu - San Diego CA, US
Assignee:
TAKEDA PHARMACEUTICAL COMPANY LIMITED - Osaka
International Classification:
C07D 471/04, A61K 31/497, A61K 31/4985, A61K 31/519, A61K 31/5377, C07H 17/02, A61K 31/706, A61P 35/00, A61P 25/16, A61P 25/28, A61P 29/00, A61P 19/02, A61P 9/00
US Classification:
514 27, 544279, 544117, 51421018, 51425505, 514249, 51426411, 5142342, 536 174
Abstract:
The invention relates to HSP90 inhibiting compounds consisting of the formula: (I) wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.