YI ZHANG, ANP-BC
Nursing at Benedict Dr, Dulles, VA

License number
Virginia 0024170479
Category
Nursing
Type
Adult Health
Address
Address 2
46440 Benedict Dr SUITE 107, Dulles, VA 20164
PO Box 17334, Baltimore, MD 21297
Phone
(703) 450-1125
(703) 450-1145 (Fax)
(703) 443-6717
(703) 443-8643 (Fax)

Professional information

Yi Zhang Photo 1

Senior Radiochemist At Clinical Center/ Nih

Position:
Senior Radiochemist at Clinical Center/ NIH
Location:
Baltimore, Maryland Area
Industry:
Research
Work:
Clinical Center/ NIH - Bethesda, MD 20892 since Oct 2012 - Senior Radiochemist NIMH/NIH May 2008 - Oct 2012 - Senior Chemist JHBMC/NIDA/NIH Apr 2004 - May 2008 - research scientist
Education:
New Mexico State University 1996 - 2001
Ph.D., Organic Chemistry
Nan Kai University 1986 - 1993
Master's degree, Physical Chemistry
Skills:
NMR, HPLC, Organic Synthesis, Purification, Medicinal Chemistry, Drug Discovery, Spectroscopy, Analytical Chemistry, Fluorescence, Mass Spectrometry, Organic Chemistry, NMR spectroscopy, UV/Vis


Yi Zhang Photo 2

Self-Sustained Fluidic Droplet Cassette And System For Biochemical Assays

US Patent:
2013009, Apr 18, 2013
Filed:
Jul 26, 2011
Appl. No.:
13/805625
Inventors:
Seungkyung Park - Pikesville MD, US
Samuel Yang - Ellicott City MD, US
Yi Zhang - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
C12Q 1/68
US Classification:
506 39, 4352872
Abstract:
A fluidic cartridge for biochemical assays includes a cartridge body defining a first droplet region and a second droplet region with a droplet restraining barrier therebetween. The droplet restraining barrier has a gap between the first and the second droplet regions. The fluidic cartridge also includes a first droplet dispensed in the first droplet region. The first droplet includes a plurality of magnetic particles dispersed therein. The fluidic cartridge also includes a second droplet disposed in the second droplet region. The plurality of magnetic particles are sufficiently small to be drawn through the gap between the first and second droplet regions when compelled by an applied magnetic field, and the first droplet is restrained by the restraining barrier while the plurality of magnetic particles are drawn through the gap. A biochemical assay system includes a stage adapted to receive a fluidic cartridge, and a magnetic control assembly that includes a magnet. The magnet of the magnetic control assembly is movable to direct motion of magnetic particles contained within the fluidic cartridge.


Yi Zhang Photo 3

Unified System And Method For Animal Behavior Characterization In Home Cages Using Video Analysis

US Patent:
2009028, Nov 19, 2009
Filed:
Jan 15, 2009
Appl. No.:
12/354727
Inventors:
Yiqing LIANG - Vienna VA, US
Vikrant KOBLA - Ashburn VA, US
Xuesheng BAI - Ashburn VA, US
Yi ZHANG - Baltimore MD, US
Linda S. Crnic - Denver CO, US
Stan L. Wilks - Denver CO, US
Wayne Wolf - Atlanta GA, US
Assignee:
CLEVER SYS, INC. - Reston VA
International Classification:
G06K 9/00
US Classification:
382110
Abstract:
Systems and methods for finding the position and shape of an animal using video are disclosed. The invention includes a system with a video camera coupled to a computer in which the computer is configured to automatically provide animal segmentation and identification, animal motion tracking (for moving animals), animal posture classification, and behavior identification. In a preferred embodiment, the present invention may use background subtraction for animal identification and tracking, and a combination of decision tree classification and rule-based classification for posture and behavior identification. Thus, the present invention is capable of automatically monitoring a video image to identify, track and classify the actions of various animals and the animal's movements within the image. The image may be provided in real time or from storage.


Yi Zhang Photo 4

System And Method Of Performing Magnetic Resonance Spectroscopic Imaging

US Patent:
2014001, Jan 16, 2014
Filed:
Mar 22, 2012
Appl. No.:
14/006069
Inventors:
Paul A. Bottomley - Baltimore MD, US
Refaat Gabr - Baltimore MD, US
Yi Zhang - Baltimore MD, US
Assignee:
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
International Classification:
G01R 33/46
US Classification:
324309, 324322
Abstract:
A method of performing spatially localized magnetic resonance spectroscopy includes receiving a magnetic resonance image of an object; identifying a plurality C of compartments that generate magnetic resonance spectroscopy signals in the object including at least one compartment of interest; segmenting in at least one spatial dimension the magnetic resonance image of the object into the C compartments; acquiring magnetic resonance spectroscopy signals from the compartments by applying a plurality of M′ phase encodings applied in the at least one spatial dimension, wherein M′≧C; calculating a spatially localized magnetic resonance chemical shift spectrum from the at least one compartment of interest; and rendering a spatially localized magnetic resonance spectrum that is substantially equal to a spatial average of magnetic resonance chemical shift spectra from the at least one compartment of interest. A magnetic resonance spectroscopy and imaging system is configured to perform the above method.


Yi Zhang Photo 5

Unified System And Method For Animal Behavior Characterization From Top View Using Video Analysis

US Patent:
7817824, Oct 19, 2010
Filed:
Feb 3, 2009
Appl. No.:
12/365149
Inventors:
Yiqing Liang - Vienna VA, US
Vikrant Kobla - Ashburn VA, US
Xuesheng Bai - Ashburn VA, US
Yi Zhang - Baltimore MD, US
Linda S Crnic - Denver CO, US
Wayne Wolf - Atlanta GA, US
Assignee:
Clever Sys, Inc. - Reston VA
International Classification:
G06K 9/00, G06K 9/34, G06K 9/48, G06K 9/36, G06K 9/40, A61K 49/00, H04N 1/46
US Classification:
382110, 382173, 382199, 382266, 382291, 358538, 424 91
Abstract:
In general, the present invention is directed to systems and methods for finding the position and shape of an animal using video. The invention includes a system with a video camera coupled to a computer in which the computer is configured to automatically provide animal segmentation and identification, animal motion tracking (for moving animals), animal feature points and segments identification, and behavior identification. In a preferred embodiment, the present invention may use background subtraction for animal identification and tracking, and a combination of decision tree classification and rule-based classification for feature points and segments and behavior identification. Thus, the present invention is capable of automatically monitoring a video image to identify, track and classify the actions of various animals and the animal's movements within the image. The image may be provided in real time or from storage. The invention is particularly useful for monitoring and classifying animal behavior for testing drugs and genetic mutations, but may be used in any of a number of other surveillance applications.


Yi Zhang Photo 6

Fluidic Chips Having Surface Energy Traps

US Patent:
2013030, Nov 14, 2013
Filed:
Apr 3, 2013
Appl. No.:
13/856320
Inventors:
Jeff Tza-Huei Wang - Timonium MD, US
Yi Zhang - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
C12Q 1/68
US Classification:
506 9, 216 41, 216 45, 435 612, 4352872
Abstract:
A method of using a fluidic device includes providing a fluidic chip having a plurality of surface energy traps; depositing at least one fluid droplet on the fluidic chip, the fluid droplet including magnetic particles suspended therein; and moving at least a portion of the at least one fluid droplet across a surface of the fluidic chip by altering a magnetic interaction applied to the magnetic particles such that the at least one fluid droplet interacts with at least one of the plurality of surface energy traps.


Yi Zhang Photo 7

Device And Method For Preparing And Performing Multiple Polymerase Chain Reactions

US Patent:
2010024, Sep 23, 2010
Filed:
Mar 2, 2010
Appl. No.:
12/716031
Inventors:
Jeff Tza-Huei Wang - Timonium MD, US
Yi Zhang - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
C12Q 1/68, C12M 1/34, B05D 3/00
US Classification:
435 6, 4352871, 4273722
Abstract:
The present invention relates to methods, kits and devices with multiple open reaction chambers having multiple pre-deposited primer compositions, and a basic sample loading mechanism that utilizes an immiscible companion fluid for preparing and performing multiple Polymerase Chain Reactions


Yi Zhang Photo 8

Compositions And Methods For Polynucleotide Extraction And Methylation Detection

US Patent:
2011016, Jul 7, 2011
Filed:
Jan 5, 2009
Appl. No.:
12/811581
Inventors:
Stephen Baylin - Baltimore MD, US
James Gordon Herman - Lutherville MD, US
Vasudev Bailey - Baltimore MD, US
Hariharan Easwaran - Baltimore MD, US
Hetty Carraway - Baltimore MD, US
Yi Zhang - Baltimore MD, US
Brian P. Keeley - Rockford MI, US
Assignee:
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
International Classification:
C12Q 1/68, C07H 1/06
US Classification:
435 611, 435 61, 536 2541
Abstract:
The present invention features methods and compositions for methylation detection, as well as a novel method for polynucleotide extraction and sodium bisulfite treatment.