Inventors:
Yang Wang - Westford MA, US
International Classification:
B01D 59/44, H01J 49/00
US Classification:
250288, 250281, 250282, 250283, 250287, 250423 R, 250424, 250324, 422907, 436173
Abstract:
Combined desorption and ionization sources are provided to generate molecular ions form a sample disposed on a substrate surface. A heated gas-jet probe or heated solvent stream probe desorbs sample molecules into the gas phase. The desorbed sample molecules are ionized by reaction between the sample molecule and charged solvent droplets. The charged solvent droplets may be produced by electrospray probe or by a corona discharge. The combined desorption and ionization sources coupled by a vacuum interface to a mass spectrometer, where the sample molecule ions can be analyzed.