DR. XITONG LI, PH.D, L.AC
Acupuncture at Main St, Milpitas, CA
License number
California AC 11354
Category
Acupuncture
Type
Acupuncturist
Address
Address
2
1669 S Main St, Milpitas, CA 95035
278 Bonny St, Mountain View, CA 94043
278 Bonny St, Mountain View, CA 94043
Phone
(408) 942-7479
Professional information
Gene Expression Profile Algorithm And Test For Likelihood Of Recurrence Of Colorectal Cancer And Response To Chemotherapy
US Patent:
2010028, Nov 11, 2010
Filed:
Apr 30, 2010
Appl. No.:
12/772136
Inventors:
Steven Shak - Hillsborough CA, US
Drew Watson - Los Altos CA, US
Xitong Li - Mountain View CA, US
Lawrence Lee - Redwood City CA, US
Kim Langone - Sunnyvale CA, US
Drew Watson - Los Altos CA, US
Xitong Li - Mountain View CA, US
Lawrence Lee - Redwood City CA, US
Kim Langone - Sunnyvale CA, US
International Classification:
C40B 30/02, C12Q 1/68
US Classification:
506 8, 435 6
Abstract:
Algorithm-based molecular assays that involve measurement of expression levels of prognostic and/or predictive genes, or co-expressed genes thereof, from a biological sample obtained from a cancer patient, and analysis of the measured expression levels to provide information concerning the likelihood of recurrence of colorectal cancer and/or the likelihood of a beneficial response to chemotherapy for the patient are provided herein. Methods of analysis of gene expression values of prognostic and/or predictive genes, as well as methods of identifying gene expression-tumor region ratios, tumor-associated stromal surface area, and gene cliques, i.e. genes that co-express with a validated biomarker and thus may be substituted for that biomarker in an assay, are also provided.
Dr. Xitong Li, Milpitas CA - PHD
Specialties:
Acupuncture
Address:
1669 S Main St, Milpitas 95035
(408) 942-7479 (Phone)
(408) 942-7479 (Phone)
Languages:
English
Xitong Li, Milpitas CA
Specialties:
Acupuncturist
Address:
1669 S Main St, Milpitas, CA 95035
Method And System To Characterize Transcriptionally Active Regions And Quantify Sequence Abundance For Large Scale Sequencing Data
US Patent:
8566039, Oct 22, 2013
Filed:
May 15, 2008
Appl. No.:
12/121412
Inventors:
Xitong Li - Mountain View CA, US
Kenneth Stineman - San Jose CA, US
Kenneth Stineman - San Jose CA, US
Assignee:
Genomic Health, Inc. - Redwood City CA
International Classification:
G01N 33/48, G06F 19/00
US Classification:
702 19, 702 20
Abstract:
This invention provides a quantitative method to determine transcriptionally active regions and quantify sequence abundance from large scale sequencing data. The invention also provides a system based on reference sequences to design and implement the method. The system processes large scale sequence data from high throughput sequencing, generates transcriptionally active region sequences as necessary, and quantifies the sequence abundance of the gene or transcriptionally active region. The method and system are useful for many analyses based on RNA expression profiling.
Qrt-Pcr Assay System For Gene Expression Profiling
US Patent:
2005009, May 5, 2005
Filed:
Oct 11, 2004
Appl. No.:
10/963286
Inventors:
Joffre Baker - Montara CA, US
Maureen Cronin - Los Altos CA, US
Michael Kiefer - Clayton CA, US
Xitong Li - Mountain View CA, US
Kim Clark - Mountain View CA, US
Maureen Cronin - Los Altos CA, US
Michael Kiefer - Clayton CA, US
Xitong Li - Mountain View CA, US
Kim Clark - Mountain View CA, US
Assignee:
Genomic Health Inc. - Redwood City CA
International Classification:
C12Q001/68, C12P019/34
US Classification:
435006000, 435091200
Abstract:
The invention concerns an integrated, qRT-PCR-based system for analyzing and reporting RNA expression profiles of biological samples. In particular, the invention concerns a fully optimized and integrated multiplex, multi-analyte method for expression profiling of RNA in biological samples, including fixed, paraffin-embedded tissue samples. The gene expression profiles obtained can be used for the clinical diagnosis, classification and prognosis of various pathological conditions, including cancer.
Method For Quantitative Pcr Data Analysis System (Qdas)
US Patent:
2006000, Jan 12, 2006
Filed:
Jul 6, 2004
Appl. No.:
10/886501
Inventors:
Xitong Li - Mountain View CA, US
Kenneth Stineman - San Jose CA, US
Kenneth Stineman - San Jose CA, US
Assignee:
Genomic Health - Redwood City CA
International Classification:
C12Q 1/68, G06F 19/00
US Classification:
435006000, 702020000
Abstract:
This invention provides a method for the quantitation and quality assurance of QPCR data. In particular, the invention provides a method for extracting data curves from a QPCR assay, estimating the shape and characteristics of an amplification curve and producing a quality score metric. The invention also provides a robust method for calculating a threshold cycle (C) value and classifying the status of the QPCR results.
Quantitative Pcr Data Analysis System (Qdas)
US Patent:
2006000, Jan 12, 2006
Filed:
Jul 6, 2004
Appl. No.:
10/886019
Inventors:
Xitong Li - Mountain View CA, US
Kenneth Stineman - San Jose CA, US
Kenneth Stineman - San Jose CA, US
International Classification:
C12Q 1/68, G06F 19/00
US Classification:
702020000, 435006000
Abstract:
A system for measuring data includes a first processor for extracting data curves from an assay. The first processor estimates a Quality Score (QS) based on the shape and variation of an amplification curve. A second processor calculates a threshold cycle (C) value. The Cvalue is the fractional cycle number at which the assay signal rises above a threshold. The processor makes a status classification of the amplification curve. A database is provided to store the QS, C, and classification results.