WILLIAM ROBERT SKACH, MD
Osteopathic Medicine at Sam Jackson Park Rd, Portland, OR
License number
Oregon MD15063
Category
Osteopathic Medicine
Type
Hematology & Oncology
Address
Address
3181 SW Sam Jackson Park Rd, Portland, OR 97239
Phone
(503) 494-7322
Personal information
See more information about WILLIAM ROBERT SKACH at radaris.comName
Address
Phone
13640 NW Springville Ln, Portland, OR 97229
13640 Springville Ln, Portland, OR 97229
4855 Stephenson St, Portland, OR 97219
Professional information
See more information about WILLIAM ROBERT SKACH at trustoria.com
Dr. William R Skach, Portland OR - MD (Doctor of Medicine)
Dr. William R Skach, Portland OR - MD (Doctor of Medicine)
Specialties:
Hematology, Medical Oncology, Oncology
Address:
3181 SW Sam Jackson Park Rd SUITE R, Portland 97239
(503) 494-6594 (Phone), (503) 494-8393 (Fax)
OREGON HEALTH AND SCIENCE UNIVERSITY
3181 SW Sam Jackson Park Rd, Portland 97239
(503) 494-8311 (Phone), (503) 494-3092 (Fax)
HEMATOLOGY & ONCOLOGY CLINIC
3181 SW Sam Jackson Park Rd, Portland 97239
(503) 494-8534 (Phone), (503) 494-4285 (Fax)
OHSU
3181 SW Sam Jackson Park Rd SUITE R, Portland 97239
(503) 494-8311 (Phone)
(503) 494-6594 (Phone), (503) 494-8393 (Fax)
OREGON HEALTH AND SCIENCE UNIVERSITY
3181 SW Sam Jackson Park Rd, Portland 97239
(503) 494-8311 (Phone), (503) 494-3092 (Fax)
HEMATOLOGY & ONCOLOGY CLINIC
3181 SW Sam Jackson Park Rd, Portland 97239
(503) 494-8534 (Phone), (503) 494-4285 (Fax)
OHSU
3181 SW Sam Jackson Park Rd SUITE R, Portland 97239
(503) 494-8311 (Phone)
Certifications:
Hematology, 1990, Internal Medicine, 1986, Medical Oncology, 1991
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Harvard Med Sch
Graduated: 1983
U Calif
Harvard Med Sch
Graduated: 1983
U Calif
Professor At Ohsu
Professor At Ohsu
Location:
Portland, Oregon Area
Industry:
Hospital & Health Care
Experience:
OHSU (Educational Institution; 10,001+ employees; Hospital & Health Care industry): Professor, (-)
William Robert Skach, Portland OR
William Robert Skach, Portland OR
Specialties:
Internal Medicine, Hematology & Oncology
Work:
Oregon Health & Science University
3181 SW Sam Jackson Park Rd, Portland, OR 97239
3181 SW Sam Jackson Park Rd, Portland, OR 97239
Education:
Harvard University(1983)
Use Of Cysteine-Derived Suppressor Trnas For Non-Native Amino Acid Incorporation
Use Of Cysteine-Derived Suppressor Trnas For Non-Native Amino Acid Incorporation
US Patent:
2012007, Mar 29, 2012
Filed:
May 5, 2011
Appl. No.:
13/101993
Inventors:
William Skach - Portland OR, US
Zhongying Yang - Beaverton OR, US
Soo Jung Kim - Portland OR, US
Jacob Gubbens - Oegstgeest, NL
Arthur Johnson - College Station TX, US
Zhongying Yang - Beaverton OR, US
Soo Jung Kim - Portland OR, US
Jacob Gubbens - Oegstgeest, NL
Arthur Johnson - College Station TX, US
International Classification:
C12P 21/00, C12Q 1/68, C07H 21/02
US Classification:
435 61, 536 231, 435 681
Abstract:
Disclosed herein are compositions and methods for incorporating non-native amino acids into a single polypeptide. In one example, an isolated modified suppressor tRNA is disclosed that includes the following: a modified tRNA, wherein the tRNAhas been modified so that an anticodon of the tRNA is complementary to a stop codon; a cysteine amino acid residue is covalently linked to the modified tRNAby aminoacylation generating a chemically reactive sulfhydryl side chain; and a detectable label is covalently linked to the sulfhydryl side chain. Methods for incorporating non-native amino acids into a single polypeptide utilizing the disclosed isolated modified suppressor tRNAs are also disclosed.