Inventors:
William R. LEVIS - New York NY, US
Frank T. MARTINIUK - Wood-Ridge NJ, US
Assignee:
NEW YORK UNIVERSITY - New York NY
International Classification:
A61K 38/16, A61K 39/04, C07H 21/04, C07K 14/35, C07K 16/12, A61P 35/00, A61P 31/08, A61P 17/00, A61P 27/14, C12N 5/10, C12N 1/21, C12N 7/00, A61K 39/395, G01N 33/53, C12Q 1/68
US Classification:
4241391, 4241901, 514 12, 536 237, 530350, 536 234, 5303879, 435325, 4352523, 4352351, 4352542, 435348, 435419, 435 71, 435 6
Abstract:
The present invention is directed to heat shock proteins from as well as their encoding polynucleotides and vectors and host cells containing these polynucleotides. These heat shock proteins and their encoding polynucleotides are useful in detection of . In addition, the heat shock protein can be used as an adjuvant in a pharmaceutical composition containing an antigen to induce or enhance the immune response against the antigen. Further, the heat shock protein may be used to treat atopic conditions or as a vaccine against . Alternatively, the heat shock protein can be used to form a fusion protein with an antigen to induce or enhance the immune response against the antigen.