WILLIAM ROBERT KRAUSE
Pilots at Gilliams Mtn Rd, Charlottesville, VA

6258093, Jul 10, 2001

Jan 28, 2000

9/494108

Garland U. Edwards - Midlothian VA
William R. Krause - Charlottesville VA

A61B 1900

606 80

The invention provides a cutter head that reduces the cutting force and number of reamers required by increasing the depth of cut or cutting length. The cutting head uses at least one tooth placed along the length of flutes formed within the body of the cutting head. The grooves forming the flutes can follow a first helical path along the body length, maintaining a substantially constant path over a major portion of the entire length in relation to the axes or, alternatively, have a constantly changing path. A second pattern can follow a second, contiguous helical path that has a second radial orientation to the axis. The teeth can be formed from a sinusoidal wave form comprised of a continuous radius going from convex to concave, with each of the teeth having a predetermined pitch from the crest to the base. In another embodiment the crest of the teeth on the first flute is offset axially by a predetermined distance from the teeth on the adjacent flutes. The offset can be determined by dividing the pitch on each flute by the number of flutes.

6503249, Jan 7, 2003

Jun 13, 2000

09/592771

William R. Krause - Charlottesville VA 22903

A61B 1756

606 62, 606 86, 606 87, 606 96

The invention discloses a two- or three-axis transmitter positioner driven by a pulsed DC current, external to the patient, coupled with three- or two-axis receivers positioned internal and/or external to the implant. The receivers are sensitive to a transmitted DC magnetic field emanating from the activated transmitter. Receiver signal processing electronics control the receiver and serve to convert its output to a format suitable for processing by a digital computer in conjunction with a method for processing received signals so as to thereby develop position and orientation data of the transverse locking holes or pin placement. Such data then can be graphically displayed to the user so as to guide the user for accurate alignment of a drill bit with the transverse holes in the implanted device.

6447518, Sep 10, 2002

Apr 25, 2000

09/557607

William R. Krause - Charlottesville VA 22903
Garland U. Edwards - Midlothian VA 23113

A61B 1716

606 80

An improved flexible shaft used in the reaming of the medullary space in bones is described. The shaft is comprised of a solid element with a longitudinal bore the entire length and an appropriately formed slot which extends spirally around the shaft either continuously or segmentally. Attached to the shafts opposite ends respectively, are a cutting head and a means of connecting the shaft to a driving mechanism. Additionally, an improved anthropomorphic spinal element and vertebral body replacement implant are described. The anthropomorphic spinal element is composed of a solid element with a longitudinal bore and an appropriately formed slot that extends spirally around the shaft either continuously or segmentally and is completely or partially filled with an elastomeric material. The vertebral body replacement implant is composed of a suitable implant material with a longitudinal bore the entire length and an appropriately formed slot which extends spirally around the shaft either continuously or segmentally. Attached to the central sections opposite ends are a means of attachment to the adjacent vertebra allowing for height and angular adjustment.

2008022, Sep 11, 2008

Feb 14, 2008

12/069934

William R. Krause - Charlottesville VA, US

A61B 17/04, A61B 17/70

606255, 606246, 606300

An improved flexible component used for dynamic stabilization of spinal segments for the treatment of vertebrae deformities and injuries and for the replacement of a complete or segment of the body of a vertebra in the spine is described. The flexible component is comprised of a solid, suitable implant material with a longitudinal bore the entire length and an appropriately formed slot which extends spirally around the shaft either continuously or segmentally. The flexible component may be encapsulated, fully or partially, in a suitable implant grade elastomeric resilient material. When used for a dynamic stabilization device, the component is attached to the vertebral bodies by pedicle screws know to those in the art. When used as a vertebral replacement device, attached to the component's opposite ends are members for attachment to the adjacent vertebra that allow for height and angular adjustment.

6074394, Jun 13, 2000

Jan 27, 1998

9/013827

William R. Krause - Charlottesville VA

A61F 228, A61F 202, A61F 500, A61B 1758

606 86

A method of securing an implant into a bone using a targeting device having at least two magnetic field communication units are disclosed. The device consists of at least a receiver and transmitter for multi-axis pulsed direct current magnetic signals in each of three orthogonal planes. One of the communication units carried in a fixed position by a drill guide and a second of the communication units is in a fixed, offset position relative to an implant connector. The position and orientation of the drill guide relative to the implant connector is determined by the transmission of the pulsed direct current magnetic signal from the transmitting unit and receiving that signal at the receiver. The signals provide the position and location of the communication units in relation to one another. The signals are converted into position and orientation data format readable by a programmed computer.

8353935, Jan 15, 2013

Jul 3, 2009

12/497593

William R. Krause - Charlottesville VA, US

A61B 17/70

606255

The invention relates to a flexible spine stabilization and/or vertebral replacement system and having one or more flexible segments within a spinal element. The flexibility is created through the use of at least one circumferential slot formed in the spinal element. One or more fasteners are connected to the distal and proximal attachments and secured to the vertebra. The spinal element can have an elastomeric material in any or all of the following combinations: filling at least one of the at least one slot; at least a portion of the inside core; encompass at least a portion of the exterior diameter. Vertebral replacement is achieved by securing the spinal element to healthy inferior and superior vertebra through use of securing members.

7963928, Jun 21, 2011

Dec 13, 2006

11/638114

William R. Krause - Charlottesville VA, US

A61B 10/00

600562, 600568

An automated device for obtaining a tissue biopsy and delivering material to provide hemostatis, therapeutic agents or marker material is described. The device has an outer casing, a power source, a drive mechanism, an application chamber through which the biopsy mechanism, typically a cutting needle, passes through and an application channel. The cutting biopsy mechanism has a mechanical or electromechanical mechanism to rapidly fire a stylet with a biopsy trough into the intended tissue and then rapidly propel a biopsy cannula over the stylet to sever and retain tissue that has protruded into the biopsy trough. At least one application channel is formed by a tube centrically slipped over the biopsy cannula wall. To enable the collection of tissue specimens, the distal segment of the application channel forms a close fitting and concentric sheath around the biopsy cannula.

2011014, Jun 16, 2011

Feb 24, 2010

12/712174

William R. Krause - Charlottesville VA, US
Mike Fard - Charlottesville VA, US

A61B 17/86

606309

A flexible compression screw having multiple segments, one or more of which are flexible and one or more segments that also include threads. The flexibility is created through the use of at least one helical slot formed generally in the center segment of the element. Additional flexible segments also have at least one helical slot in either the same helical rotation and pattern or in an opposite rotation and/or different pattern. An elastomeric material can fill the hollow body, extend into the slots and/or encompass the exterior. The flexible screw can have a hollow body, including leading and trailing edge, or can have a partially hollow body.

5490852, Feb 13, 1996

Feb 16, 1994

8/197078

Samir N. Azer - Alexandria VA
William R. Krause - Charlottesville VA

A61B 1716

606 79

An awl for providing entry into and subsequent penetration of a bone is disclosed. The awl features a first section which is straight and has a first end, an exterior end, and a cutting tip at its exterior end. The second section of the awl is a connection region which has a first end and a second end. The first end of the second section extends essentially normal from the first end of the first section. The third section provides an external reference for the direction of the cutting tip and extends from the second end of the second section in a direction essentially parallel to the first section, such that the oriention of the third section represents the orientation of the first section.