WILLIAM RILEY SCHOEN
Pilots at Fld Brk Rd, Madison, CT

License number

Connecticut A2483463

Issued Date

Apr 2016

Expiration Date

Apr 2018

Professional information

Benzofuran And Dihydrobenzofuran Derivatives Useful As Beta-3 Adrenoreceptor Agonists

US Patent:

6780859, Aug 24, 2004

Filed:

Sep 10, 2002

Appl. No.:

10/241250

Inventors:

Gaetan H. Ladouceur - Branford CT
William R. Schoen - Madison CT
Michael J. Burke - West Haven CT

Assignee:

Bayer Pharmaceuticals Corporation - West Haven CT

International Classification:

A61K 3165

US Classification:

5142335, 51425213, 514337, 514365, 544153, 544376, 546196, 548202, 548215, 5483114, 549467

Abstract:

This invention relates to novel benzofuran and dihydrobenzofuran compounds, pharmaceutical compositions containing such compounds, and methods of treating beta-3 adrenoreceptor-mediated conditions with such compositions.

Substituted 4-Biarylbutyric And 5-Biarylpentanoic Acid Derivatives As Matrix Metalloprotease Inhibitors

US Patent:

6288063, Sep 11, 2001

Filed:

May 27, 1998

Appl. No.:

9/085909

Inventors:

Harold Clinton Eugene Kluender - Trumbull CT
David Ross Brittelli - Branford CT
William Riley Schoen - Madison CT
Sookhee Nicole Ha - Woodbridge CT

Assignee:

Bayer Corporation - Pittsburgh PA

International Classification:

C07D20948, C07D29518, A61K 3112, A61K 3116

US Classification:

514243

Abstract:

Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have the generalized formula (T). sub. x A--B--D--E--G wherein A is an aryl or heteroaryl rings; B is an aryl or heteroaryl ring or a bond; each T is a substituent group; x is 0, 1, or 2; the group D represents ##STR1## the group E represents a two or three carbon chain bearing one to three substituent groups which are independent or are involved in ring formation, possible structures being shown in the text and claims; and the group G represents ##STR2## and with the proviso that when G is ##STR3## each of the substituents on E is an independent substituent; and include pharmaceutically acceptable salts thereof.

Substituted Biphenyls

US Patent:

6218431, Apr 17, 2001

Filed:

Jul 31, 1997

Appl. No.:

8/904119

Inventors:

William R. Schoen - Madison CT
Gaetan H. Ladouceur - Branford CT
James H. Cook - East Hampton CT
Timothy G. Lease - Guilford CT
Donald J. Wolanin - Orange CT
Richard H. Kramss - Guilford CT
Donald L. Hertzog - Madison CT
Martin H. Osterhout - Raleigh NC

Assignee:

Bayer Corporation - Pittsburgh PA
Bayer Aktiengesellschaft - Leverkusen

International Classification:

A61K 31275, C07C25554, C07C 3928, C07C 3910

US Classification:

514520

Abstract:

Substituted biphenyls having glucagon receptor antagonistic activity. Claimed compounds have the formula ##STR1## wherein R. sup. 1a and R. sup. 1b independently represent (C. sub. 1 -C. sub. 6) alkyl; R. sup. 2 represents (C. sub. 1 -C. sub. 10) alkyl or substituted (C. sub. 1 -C. sub. 10) alkyl wherein the substituents are independently from 1 to 3 of --SR. sup. 7 ; R. sup. 7 represents phenyl, or substituted phenyl wherein the substituents are independently 1-5 of halogen, trifluoromethyl, (C. sub. 1 -C. sub. 6) alkyl, (C. sub. 1 -C. sub. 6) alkoxy, nitro, cyano, or hydroxyl; R. sup. 3 represents substituted (C. sub. 1 -C. sub. 6) alkyl wherein the substituents are 1-2 hydroxyl groups; G represents a substituent selected from the group consisting of halogen, (C. sub. 1 -C. sub. 6) alkyl, and OR. sup. 4 wherein R. sup.