Inventors:
Christopher W. Boyce - Flemington NJ, US
Sylvia Joanna Degrado - Scotch Plains NJ, US
Xiao Chen - Edison NJ, US
Jun Qin - Edison NJ, US
Younong Yu - East Brunswick NJ, US
Kevin D. McCormick - Basking Ridge NJ, US
Anandan Palani - Bridgewater NJ, US
Dong Xiao - Warren NJ, US
Robert George Aslanian - Rockaway NJ, US
Jie Wu - Scotch Plains NJ, US
Ashwin Umesh Rao - Morganville NJ, US
Phieng Siliphaivanh - Newton MA, US
Joey L. Methot - Westwood MA, US
Hongjun Zhang - Newton MA, US
Elizabeth Helen Kelley - Lynnfield MA, US
William Colby Brown - Cleveland Heights OH, US
Qin Jiang - Latham NY, US
Jolicia Polivina Gauuan - Schenectady NY, US
Andrew J. Leyhane - Latham NY, US
Purakkattle Johny Biju - Piscataway NJ, US
Pawan K. Dhondi - Elizabeth NJ, US
Li Dong - Lawrenceville NJ, US
Salem Fevrier - Cranford NJ, US
Xianhai Huang - Warren NJ, US
Henry M. Vaccaro - South Plainfield NJ, US
International Classification:
C07D 241/42, C07D 401/12, C07D 403/06, C07D 471/04, A61K 31/4985, C07D 471/10, C07D 405/12, C07D 401/14, A61K 31/506, A61K 31/55, C07D 417/12, C07D 498/04, C07D 491/107, A61K 45/06, A61K 31/498
US Classification:
51421018, 544353, 514249, 544350, 544230, 51421021, 544295, 540523, 51421207
Abstract:
The invention provides certain quinoxalines and aza-quinoxalines of the Formula (I), and their pharmaceutically acceptable salts, wherein J, J, R, R, R, R, R, R, R, R, X, Y, b, n, and q are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTHfunction.