WILLIAM HIKARU MATSUI, M.D.
Osteopathic Medicine at Wolfe St, Baltimore, MD
License number
Maryland D53335
Category
Osteopathic Medicine
Type
Medical Oncology
Address
Address
600 N Wolfe St, Baltimore, MD 21287
Phone
(410) 933-7400
(410) 955-8964
(410) 955-8964
Personal information
See more information about WILLIAM HIKARU MATSUI at radaris.comName
Address
Phone
105 Bellemore Rd, Baltimore, MD 21210
619 Sussex Rd, Towson, MD 21286
Professional information
Associate Professor At Johns Hopkins School Of Medicine
Position:
Associate Professor at Johns Hopkins School of Medicine
Location:
Baltimore, Maryland Area
Industry:
Research
Work:
Johns Hopkins School of Medicine
since Dec 2008
-
Associate Professor
Johns Hopkins Univeristy School of Medicine
Jul 2002 - Jun 2008
-
Assistant Professor
Johns Hopkins University School of Medicine
Dec 2001 - Jun 2002
-
Instructor of Oncology
Education:
University of California, San Francisco - School of Medicine 1990 - 1995
MD, Medicine Harvard College 1985 - 1989
AB, Biochemistry
MD, Medicine Harvard College 1985 - 1989
AB, Biochemistry
Skills:
Cancer, Stem Cell Research, Stem Cell Transplant, Cancer Stem Cells, Developmental Biology, Translational Research, Oncology, Translational Medicine, Cancer Research, Stem Cells, Flow Cytometry, Cell Biology, Genomics, PCR, Genetics, Immunohistochemistry, Neuroscience, Animal Models, Molecular Biology, Epigenetics, Medical Research, Tissue Culture, Lifesciences, Immunology, Biochemistry, Protein Chemistry
Urothelial Differentiation Of Urothelial Carcinoma: A Bladder Cancer Stem Cell Model
US Patent:
2009004, Feb 19, 2009
Filed:
Mar 24, 2008
Appl. No.:
12/079078
Inventors:
David M. Berman - Towson MD, US
William Matsui - Baltimore MD, US
Xiaobing He - Baltimore MD, US
William Matsui - Baltimore MD, US
Xiaobing He - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61K 51/08, A61P 35/00, A61K 39/395, A61B 5/055, A61K 49/00, A61K 51/10
US Classification:
424 149, 4241301, 424 93, 424 96, 424 111, 4241781, 4241831
Abstract:
The present invention provides a method of treating cancer in a patient (e.g., a human patient) in need thereof, the method comprising administering a therapeutically effective regimen, the regimen comprising administering to a patient in need thereof a compound that targets 67 laminin receptor (67LR). In a particular embodiment, the compound that targets 67LR is an antibody or antibody fragment. In particular, the present invention provides a method of treating cancer comprising administering to a patient in need thereof an antibody that binds to 67LR. The present invention also provides a method of treating cancer comprising administering to a patient in need thereof an antibody conjugate, wherein the antibody conjugate comprises an antibody that binds to 67LR linked to a therapeutic agent, a protein toxin, a cytotoxic agent or other moiety. The present invention provides pharmaceutical compositions for the treatment of cancer comprising an antibody that binds to 67LR in an amount effective to reduce cancer stem cells and/or cancer cells in a patient. The invention also provides for means to detect and monitor cancer stem cells based on their expression of 67LR.
Dr. William H Matsui, Baltimore MD - MD (Doctor of Medicine)
Specialties:
Oncology, Medical Oncology
Address:
Baltimore Office
600 N Wolfe St, Baltimore 21287
(410) 955-3071 (Phone)
Sidney Kimmel Comprhsv Cncr Ctr
1800 Orleans St, Baltimore 21287
(410) 955-8964 (Phone)
600 N Wolfe St, Baltimore 21287
(410) 955-3071 (Phone)
Sidney Kimmel Comprhsv Cncr Ctr
1800 Orleans St, Baltimore 21287
(410) 955-8964 (Phone)
Certifications:
Internal Medicine, 1998, Medical Oncology, 2000
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Baltimore Office
600 N Wolfe St, Baltimore 21287
Sidney Kimmel Comprhsv Cncr Ctr
1800 Orleans St, Baltimore 21287
The Johns Hopkins Hospital
1800 Orleans St, Baltimore 21287
600 N Wolfe St, Baltimore 21287
Sidney Kimmel Comprhsv Cncr Ctr
1800 Orleans St, Baltimore 21287
The Johns Hopkins Hospital
1800 Orleans St, Baltimore 21287
Education:
Medical School
University of California At San Francisco
Graduated: 1994
Johns Hopkins University School Med
University Of Wa School Of Med
University of California At San Francisco
Graduated: 1994
Johns Hopkins University School Med
University Of Wa School Of Med
William H Matsui, Baltimore MD
Specialties:
Internal Medicine, Hematology & Oncology, Geriatric Medicine, Medical Oncology, Surgery
Work:
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
401 N Broadway St, Baltimore, MD 21287 JHU Oncology
600 N Wolfe St, Baltimore, MD 21287
401 N Broadway St, Baltimore, MD 21287 JHU Oncology
600 N Wolfe St, Baltimore, MD 21287
Education:
University of California at San Francisco (1995)
William Hikaru Matsui, Baltimore MD
Specialties:
Oncologist
Address:
600 N Wolfe St, Baltimore, MD 21287
600 N Wolfe, Baltimore, MD 21287
1650 Orleans St, Baltimore, MD 21287
600 N Wolfe, Baltimore, MD 21287
1650 Orleans St, Baltimore, MD 21287
Education:
Doctor of Medicine
Methods For Detecting And Monitoring Circulating Cancer Stem Cells
US Patent:
2011011, May 12, 2011
Filed:
Nov 15, 2007
Appl. No.:
12/743180
Inventors:
William Matsui - Baltimore MD, US
Assignee:
The Johns Hopkins Hospital University - Baltimore MD
International Classification:
A61K 39/395, C12Q 1/32, G01N 33/574, A61K 39/00, A61P 35/00, A61P 37/04
US Classification:
4241331, 435 26, 435 71, 4242771
Abstract:
Provided herein are compositions, methods, and kits useful for detecting whether a subject has or is likely to develop a cancer and for monitoring, staging and examining a cancer patient. Also provide herein are methods for screening compounds.
Methods Of Use For Cyclopamine Analogs
US Patent:
2011023, Sep 22, 2011
Filed:
Apr 20, 2011
Appl. No.:
13/090694
Inventors:
Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
William Matsui - Baltimore MD, US
Karen J. McGovern - Groton MA, US
Martin R. Tremblay - Melrose MA, US
Michael J. Grogan - Winchester MA, US
William Matsui - Baltimore MD, US
Karen J. McGovern - Groton MA, US
Martin R. Tremblay - Melrose MA, US
International Classification:
A61K 31/4355, A61P 35/00
US Classification:
514278
Abstract:
The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
Methods Of Use Of Cyclopamine Analogs
US Patent:
2012007, Mar 29, 2012
Filed:
Jul 27, 2011
Appl. No.:
13/191545
Inventors:
Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
William Matsui - Baltimore MD, US
Karen J. McGovern - Groton MA, US
Martin R. Tremblay - Melrose MA, US
Michael J. Grogan - Winchester MA, US
William Matsui - Baltimore MD, US
Karen J. McGovern - Groton MA, US
Martin R. Tremblay - Melrose MA, US
International Classification:
A61K 31/4355, A61P 35/02, A61P 35/00
US Classification:
514278
Abstract:
The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
Methods Of Use Of Cyclopamine Analogs
US Patent:
2013010, May 2, 2013
Filed:
May 18, 2012
Appl. No.:
13/475352
Inventors:
Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
William Matsui - Baltimore MD, US
Karen J. McGovern - Groton MA, US
Martin R. Tremblay - Melrose MA, US
Michael J. Grogan - Winchester MA, US
William Matsui - Baltimore MD, US
Karen J. McGovern - Groton MA, US
Martin R. Tremblay - Melrose MA, US
International Classification:
C07D 491/107, A61K 31/56, A61K 38/21, A61K 31/704, A61K 31/573, A61K 31/196, A61K 31/519, A61K 31/4745, A61K 31/69, A61K 31/198, A61K 31/17, A61K 31/664, A61K 31/454, A61K 31/7068, A61K 31/7076, A61K 31/4355
US Classification:
424 854, 514278, 514171, 514 34, 514249, 514 64, 514138, 514 49, 514 46
Abstract:
The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
Methods Of Use For Cyclopamine Analogs
US Patent:
2013010, May 2, 2013
Filed:
May 18, 2012
Appl. No.:
13/475510
Inventors:
Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
William Matsui - Baltimore MD, US
Karen J. McGovern - Groton MA, US
Martin R. Tremblay - Meirose MA, US
Michael J. Grogan - Winchester MA, US
William Matsui - Baltimore MD, US
Karen J. McGovern - Groton MA, US
Martin R. Tremblay - Meirose MA, US
International Classification:
C07D 491/107, A61K 31/4355, A61K 45/06
US Classification:
424 854, 514278, 514 34, 514249, 514 64, 514110, 514 49, 514 48, 514171
Abstract:
The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: