WILLIAM HEWLETT, MD, PHD
Psychiatric in Nashville, TN

License number
Tennessee MD21920
Category
Psychiatric
Type
Psychiatry
Address
Address
3601 Tvc, Nashville, TN 37232
Phone
(615) 322-3000

Organization information

See more information about WILLIAM HEWLETT at bizstanding.com

William Hewlett MD

1601 23 Ave S STE 1030, Nashville, TN 37212

Industry:
Psychiatrist
Doing business as:
William Hewlett MD,PHD
Phone:
(615) 322-6840 (Phone), (615) 322-3000 (Phone)
William Albion Hewlett
Categories:
Physicians & Surgeons
Products:
United States Air Force

Professional information

William Hewlett Photo 1

Dr. William Hewlett, Nashville TN - MD (Doctor of Medicine)

Specialties:
Child & Adolescent Psychiatry
Address:
1601 23Rd Ave S STE 1030, Nashville 37212
(615) 322-6840 (Phone)
5887 Fredricksburg Dr, Nashville 37215
VANDERBILT PSYCHIATRIC HOSPITAL
1601 23Rd Ave S STE 3105, Nashville 37212
(615) 327-7124 (Phone), (615) 327-7136 (Fax)
3601 Tvc, Nashville 37232
(615) 322-3000 (Phone)
Languages:
English
Education:
Medical School
Stanford University
Graduated: 1983
Stanford University Hospital


William A Hewlett Photo 2

William A Hewlett, Nashville TN

Specialties:
Psychiatrist
Address:
1601 23Rd Ave S, Nashville, TN 37212


William Hewlett Photo 3

Genetic And Pharmacological Regulation Of Antidepressant-Sensitive Biogenic Amine Transporters Through Pkg/P38 Map Kinase

US Patent:
2007012, May 31, 2007
Filed:
Oct 6, 2006
Appl. No.:
11/545023
Inventors:
Randy Blakely - Brentwood TN, US
Harish Prasad - Nashville TN, US
William Hewlett - Nashville TN, US
International Classification:
A61K 48/00, C12Q 1/68, G01N 33/567
US Classification:
424093210, 514002000, 514044000, 435006000, 435007200
Abstract:
The invention relates to the observation that the p38 mitogen-activated protein kinase pathway is an important regulator of biogenic amine transporter (BAT) function. By using modulator of p38 MAPK, one can alter BAT function in a specific manner. This recognition of the pathway and its interaction with the serotonin transporter (SERT) and the norepinephrine transporter (NET), along with the PPA, PKG and PDE pathways, also provides the opportunity to identify polymorphisms that will impact the efficacy of drugs that act though on these enzymes or their pathways.


William Hewlett Photo 4

A3 Adenosine Receptors As Targets For The Modulation Of Central Serotonergic Signaling

US Patent:
2009008, Apr 2, 2009
Filed:
May 7, 2008
Appl. No.:
12/116629
Inventors:
RANDY BLAKELY - Brentwood TN, US
William Hewlett - Nashville TN, US
International Classification:
A61K 31/7076, A61K 31/4422
US Classification:
514 46, 514356
Abstract:
The present invention relates to the use of adenosine type 3 receptor (A3R) modulators to modulate serotonin transporter (SERT) function in vivo. In particular, antagonists of A3R can be used to inhibit A3R-dependent upregulation of SERT, for example, as antidepressants.


William Hewlett Photo 5

Substituted Benzamides And Radioligand Analogs And Methods Of Use

US Patent:
5723103, Mar 3, 1998
Filed:
Dec 9, 1994
Appl. No.:
8/352277
Inventors:
Tomas de Paulis - Hermitage TN
Dennis E. Schmidt - Nashville TN
William Hewlett - Nashville TN
Michael H. Ebert - Nashville TN
Assignee:
Vanderbilt University - Nashville TN
International Classification:
A61K 5100, A61M 3614
US Classification:
424 185
Abstract:
This invention provides compounds of the formula I ##STR1## wherein, R. sup. 1, R. sup. 2, and R. sup. 3 are independently �a first halogen atom,! fluorine, chlorine, bromine, iodine, alkyl, alkenyl, alkynyl, alkoxy, alkenoxy, or alkynoxy, wherein R. sup. 2 and R. sup. 3 can also independently be H, wherein at least one of R. sup. 1, R. sup. 2, and R. sup. 3 is �a second halogen atom! fluorine, bromine, iodine or is substituted with �a second halogen atom,! fluorine, bromine or iodine and R. sup. 4 is H or lower alkyl. The invention also provides precursors of formula I, radioactive analogs of formula I, and methods of using the compounds for the identification of 5-HT-3 receptors and the detection and treatment of abnormal conditions associated therewith.