Inventors:
Elliot Chaikof - Atlanta GA, US
Karthik Nagapudi - Woodbridge NJ, US
William Brinkman - Atlanta GA, US
Vincent Conticello - Decatur GA, US
Robert McMillan - San Francisco CA, US
Elizabeth Wright - Los Angeles GA, US
Sonha Payne - Decatur GA, US
Assignee:
Emory University - Atlanta GA
International Classification:
A61K038/16, C07K014/00
Abstract:
Synthetic protein copolymers with plastic and elastic properties, and methods producing the copolymers, are provided. For example, a BAB triblock copolymer comprises a hydrophilic block and one or more hydrophobic blocks. The mechanical properties of a gel, fiber, fiber network, or film form of the copolymer are varied by one or more conditions before or after copolymer production. For example, a copolymer sequence can be varied before production, and one or more processing conditions such as solvent, pH, or temperature can be varied after production.