William Harlon Marshall
Dentist at Vassar Dr, Denver, CO
License number
Colorado 2490
Issued Date
Jun 1, 1956
Renew Date
Mar 1, 2016
Expiration Date
Feb 28, 2018
Type
Dentist
Address
Address
12391 E Vassar Dr, Denver, CO 80014
Professional information
Dr. William H Marshall, Aurora CO - MD (Doctor of Medicine)
Specialties:
Diagnostic Radiology, Roentgenology
Address:
12391 E Vassar Dr, Aurora 80014
(303) 873-7055 (Phone)
(303) 873-7055 (Phone)
Certifications:
Diagnostic Roentgenology
Awards:
Healthgrades Honor Roll
Languages:
English
Stabilized Polynucleotides For Use In Rna Interference
US Patent:
2004026, Dec 30, 2004
Filed:
Jul 1, 2003
Appl. No.:
10/613077
Inventors:
Devin Leake - Denver CO, US
Angela Reynolds - Denver CO, US
Anastasia Khvorova - Denver CO, US
William Marshall - Denver CO, US
Angela Reynolds - Denver CO, US
Anastasia Khvorova - Denver CO, US
William Marshall - Denver CO, US
International Classification:
A61K048/00, C07H015/24, C07H021/02, C07J017/00
US Classification:
514/044000, 536/006100, 536/023100
Abstract:
Methods and compositions for performing RNA interference comprising a wide variety of stabilized polynucleotides suitable for use in serum-containing media and for in vivo applications, such as therapeutic applications, are provided. These polynucleotides permit effective and efficient applications of RNA interference to applications such as diagnostics and therapeutics through the use of one or more modifications including orthoesters, terminal conjugates, modified linkages and 2′modified nucleotides.