Inventors:
David H. Coy - New Orleans LA
William A. Murphy - New Orleans LA
Assignee:
Administrators of the Tulane Educational Fund - New Orleans LA
International Classification:
A61K 3700, C07C10352
Abstract:
In one aspect, dodecapeptides capable of inhibiting GH, insulin, and glucagon secretion and having the formula
N-acetyl-Cys-Lys-Asn-A-Phe-D-Trp-Lys-Thr-Phe-Thr-Ser-B-NH. sub. 2
wherein A is Phe or 4-X-Phe wherein X is Cl, Br, or F, and B is Cys or D-Cys; or a pharmaceutically acceptable salt thereof.