WILLIAM H MILLER
Vehicle Board in Collegeville, PA
License number
Pennsylvania MV014264L
Category
Vehicle Board
Type
Vehicle Salesperson
Address
Address
Collegeville, PA 19426
Professional information
Vitronectin Receptor Antagonist
US Patent:
6495560, Dec 17, 2002
Filed:
Jul 12, 2001
Appl. No.:
09/857316
Inventors:
William H. Miller - Collegeville PA
Peter J. Manley - Harleysville PA
Peter J. Manley - Harleysville PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K 31435
US Classification:
514300, 514283, 546122
Abstract:
A compound of the formula (I) is disclosed which is a vitronectin receptor antagonist and is useful in the treatment of osteoporosis: or a pharmaceutically acceptable salt thereof.
Antibacterial Compounds
US Patent:
6573272, Jun 3, 2003
Filed:
Nov 28, 2001
Appl. No.:
09/980369
Inventors:
William H. Miller - Collegeville PA
Kenneth A. Newlander - West Chester PA
Mark Seefeld - Collegeville PA
Kenneth A. Newlander - West Chester PA
Mark Seefeld - Collegeville PA
Assignee:
Affinium Pharmaceuticals, Inc. - Toronto
International Classification:
A61K 31437
US Classification:
514292, 546 85, 546 86, 546 87
Abstract:
Compounds of the formula (I) are disclosed which are FabI inhibitors and are useful in the treatment bacterial infections: wherein: R is Ar or Het; R is H, C alkyl or ArâC alkyl; X is H, C alkyl, ORâ², SRâ², C alkylsulfonyl, C alkylsulfoxyl, CN, N(Râ²) , CH N(Râ²) , NO , CF , CO Râ², CON(Râ²) , CORâ², NRâ²C(O)Râ², F, Cl, Br, I, or CF S(O) â; Râ² is H, C alkyl or ArâC alkyl; and r is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.
Benzimidazoles/Imidazoles Linked To A Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity
US Patent:
5977101, Nov 2, 1999
Filed:
Dec 20, 1996
Appl. No.:
8/505171
Inventors:
Fadia El-Fehail Ali - Cherry Hill NJ
William Bondinell - Wayne PA
William Francis Huffman - Malvern PA
M. Amparo Lago - Audubon PA
Richard McCulloch Keenan - Malvern PA
Chet Kwon - King of Prussia PA
William Henry Miller - Schwenksville PA
Thomas Nguyen - King of Prussia PA
Dennis T. Takata - Flourtown PA
William Bondinell - Wayne PA
William Francis Huffman - Malvern PA
M. Amparo Lago - Audubon PA
Richard McCulloch Keenan - Malvern PA
Chet Kwon - King of Prussia PA
William Henry Miller - Schwenksville PA
Thomas Nguyen - King of Prussia PA
Dennis T. Takata - Flourtown PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K 3155, C07D40306, C07D40314
US Classification:
514221
Abstract:
Vitronectin receptor antagonists having the formula: ##STR1## which are useful for the treatment of inflammation, cancer and cardiovascular disorders, such as atherosclerosis and restenosis, and diseases wherein bone resorption is a factor, such as osteoporsis.
Integrin Receptor Antagonists
US Patent:
6008213, Dec 28, 1999
Filed:
Dec 19, 1997
Appl. No.:
8/722095
Inventors:
William E. Bondinell - Wayne PA
William H. Miller - Schwenksville PA
William H. Miller - Schwenksville PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07D23504, C07D23506, C07D21106, C07D21302
US Classification:
514211
Abstract:
Compounds of formula (I) ##STR1## wherein A. sub. 1 is C or N; E is a five- or six-membered heteroaromatic or six-membered aromatic ring optionally substituted by R. sup. 3 or R. sup. 4 ; X. sup. 1 --X. sup. 2 is CHR. sup. 1 --CH, CR. sup. 1. dbd. CH, NR. sup. 1 --CH, S(O). sub. u --CH or O--CH; X. sup. 3 is CR. sup. 5 R. sup. 5 ', NR. sup. 5, S(O). sub. u or O; R. sup. 2 is --OR', --NR'R", --NR'SO. sub. 2 R'", --NR'OR', --OCR'. sub. 2 C(O)OR', --OCR'. sub. 2 OC(O)--R', --OCR'. sub. 2 C(O)NR'. sub. 2, CF. sub. 3 or --COCR'. sub. 2 R. sup. 2 '; R. sup. 3, R. sup. 4 and R. sup. 7 are independently H, halo, --OR. sup. 12, --SR. sup. 12, --CN, --NR'R. sup. 12, --NO. sub. 2, --CF. sub. 3, CF. sub. 3 S(O). sub. r --, --CO. sub. 2 R', --CONR'. sub. 2, R. sup. 14 --C. sub.
Aminopiperidine Compounds, Process For Their Preparation, And Pharmaceutical Compositions Containing Them
US Patent:
7109213, Sep 19, 2006
Filed:
Jan 27, 2003
Appl. No.:
10/502234
Inventors:
Robert A Daines - Collegeville PA, US
William Henry Miller - Collegeville PA, US
Neil David Pearson - Harlow, GB
Israil Pendrak - Collegeville PA, US
Mark Andrew Seefeld - Collegeville PA, US
William Henry Miller - Collegeville PA, US
Neil David Pearson - Harlow, GB
Israil Pendrak - Collegeville PA, US
Mark Andrew Seefeld - Collegeville PA, US
Assignee:
Glaxo Group Limited - Greenford
International Classification:
C07D 471/02, C07D 215/16, A61K 31/44, A61K 31/47
US Classification:
514312, 313314, 313300, 546122, 546153, 546159
Abstract:
Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
Aminopiperidine Derivatives
US Patent:
7312212, Dec 25, 2007
Filed:
Jan 27, 2003
Appl. No.:
10/502233
Inventors:
Robert A Daines - Collegeville PA, US
William Henry Miller - Collegeville PA, US
Neil David Pearson - Harlow, GB
Israil Pendrak - Collegeville PA, US
Mark Andrew Seefeld - Collegeville PA, US
William Henry Miller - Collegeville PA, US
Neil David Pearson - Harlow, GB
Israil Pendrak - Collegeville PA, US
Mark Andrew Seefeld - Collegeville PA, US
Assignee:
Glaxo Group Limited - Greenford, Middlesex
International Classification:
C07D 471/04, A61K 31/4375
US Classification:
5142282, 5242285, 5242308, 524300, 524312, 524313, 524314, 544 586, 544105, 546122, 546153, 546159
Abstract:
Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
Antibacterial Agents
US Patent:
7759340, Jul 20, 2010
Filed:
Mar 26, 2009
Appl. No.:
12/411600
Inventors:
William Henry Miller - Collegeville PA, US
Meagan B. Rouse - Collegeville PA, US
Mark Andrew Seefeld - Collegeville PA, US
Meagan B. Rouse - Collegeville PA, US
Mark Andrew Seefeld - Collegeville PA, US
Assignee:
Glaxo Group Limited - Brentford, Middlesex
International Classification:
C07D 498/04, C07D 513/04, A61K 31/542, A61K 31/436
US Classification:
5142242, 5142305, 51425304, 544 48, 544105, 544362
Abstract:
Naphthyridine and quinoline derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.
Treatment Method
US Patent:
2008029, Nov 27, 2008
Filed:
Nov 29, 2006
Appl. No.:
12/094672
Inventors:
Richard Anthony Brigandi - Collegeville PA, US
Mark Levick - Collegeville PA, US
William Henry Miller - Collegeville PA, US
Mark Levick - Collegeville PA, US
William Henry Miller - Collegeville PA, US
International Classification:
A61K 31/506, A61P 9/00, A61K 31/55
US Classification:
51421207, 514275
Abstract:
The present invention is directed to methods of treating an ocular neovascular disorder in a mammal by administration of pyrimidine derivatives, benzodiazepinyl derivatives and pharmaceutical compositions containing the same. The invention encompasses methods of treating an ocular neovascular disorder by administration of 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, (S)-3-oxo-8-[3-(pyridin-2-ylamino)-1-propyloxy]-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetic acid or salts or solvates thereof. Combination therapies for the treatment of ocular neovascular disorders are also encompassed.
Fab I Inhibitors
US Patent:
7524843, Apr 28, 2009
Filed:
Jul 18, 2007
Appl. No.:
11/779578
Inventors:
William H. Miller - Collegeville PA, US
Kenneth A. Newlander - West Chester PA, US
Mark A. Seefeld - Collegeville PA, US
Irene N. Uzinskas - Villanova PA, US
Dalia R. Jakas - Norristown PA, US
Kenneth A. Newlander - West Chester PA, US
Mark A. Seefeld - Collegeville PA, US
Irene N. Uzinskas - Villanova PA, US
Dalia R. Jakas - Norristown PA, US
Assignee:
Affinium Pharmaceuticals, Inc. - Ontario
International Classification:
A61K 31/4375, C07D 265/36
US Classification:
5142305, 544105, 544333
Abstract:
Compounds of the formula (I) are disclosed which are Fab I inhibitors and are useful in the treatment of bacterial infections.
Fab I Inhibitors
US Patent:
7250424, Jul 31, 2007
Filed:
Nov 22, 2005
Appl. No.:
11/284660
Inventors:
Walter J. Burgess - Collegeville PA, US
Dalia R. Jakas - Norristown PA, US
William F. Huffman - King of Prussia PA, US
William H. Miller - Collegeville PA, US
Kenneth A. Newlander - King of Prussia PA, US
Mark A. Seefeld - Collegeville PA, US
Irene N. Uzinskas - King of Prussia PA, US
Dalia R. Jakas - Norristown PA, US
William F. Huffman - King of Prussia PA, US
William H. Miller - Collegeville PA, US
Kenneth A. Newlander - King of Prussia PA, US
Mark A. Seefeld - Collegeville PA, US
Irene N. Uzinskas - King of Prussia PA, US
Assignee:
Affinium Pharmaceuticals, Inc. - Toronto
International Classification:
A61K 31/4375, C07D 471/04
US Classification:
514300, 546122
Abstract:
Compounds are disclosed which are Fab I inhibitors and are useful in the treatment bacterial infections.