Inventors:
William C. Zamboni - Chapel Hill NC, US
Whitney Paige Caron - Carrboro NC, US
Assignee:
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL - Chapel Hill NC
International Classification:
C12Q 1/02
US Classification:
424450, 435 29, 435 721, 514 34
Abstract:
The invention provides a method of predicting the clearance rate of a carrier-mediated agent and/or the release of an agent from a carrier in a subject comprising measuring the number and/or activity of phagocytic cells and/or the amount and/or activity of opsonins and/or the amount and/or activity of complement within a biological sample obtained from a subject, and predicting the clearance rate of the carrier-mediated agent and/or the release of the agent from the carrier based upon the number and/or activity of the phagocytic cells and/or the amount and/or activity of opsonins and/or the amount and/or activity of complement.