WILLIAM C AIRD, M.D.
Osteopathic Medicine at Thorndike St, Brookline, MA
License number
Massachusetts 70959
Category
Osteopathic Medicine
Type
Internal Medicine
Address
Address
18 Thorndike St, Brookline, MA 02446
Phone
(617) 667-1031
Personal information
See more information about WILLIAM C AIRD at radaris.comName
Address
Phone
920 Depot Rd, Boxborough, MA 01719
133 Columbia St, Brookline, MA 02446
18 Thorndike St, Brookline, MA 02446
Professional information
Methods Of Inhibiting Angiogenesis Using Nadph Oxidase Inhibitors
US Patent:
2004000, Jan 1, 2004
Filed:
Apr 11, 2003
Appl. No.:
10/412783
Inventors:
William Aird - Brookline MA, US
Ruhul Abid - Belmont MA, US
Ruhul Abid - Belmont MA, US
Assignee:
Beth Israel Deaconess Medical Center, Inc. - Boston MA
International Classification:
A61K038/44, A61K031/135, A61K031/12, A61K031/03
US Classification:
424/094400, 514/646000, 514/751000, 514/689000
Abstract:
Methods of inhibiting angiogenesis, endothelial cell migration or endothelial cell proliferation, by inhibiting NADPH oxidase inhibitors, production of reactive oxygen species, or by inhibition of mRNA induction of superoxide dismutase (e.g., mitochondrial SOD), are described herein.
Methods Of Diagnosing And Treating An Inflammatory Response
US Patent:
2009019, Aug 6, 2009
Filed:
Jul 13, 2006
Appl. No.:
11/988579
Inventors:
William C. Aird - Brookline MA, US
Kiichiro Yano - Charlestown MA, US
Kiichiro Yano - Charlestown MA, US
International Classification:
A61K 38/12, C12Q 1/00, C12Q 1/68, G01N 33/53, C40B 30/00, A61K 38/28, A61K 31/56
US Classification:
514 4, 435 4, 435 6, 435 71, 506 7, 514 12, 514171
Abstract:
The present invention relates to the discovery that VEGF, PlGF, and sFlt-1 levels are increased in inflammatory response such as in sepsis, severe sepsis, or septic shock. Additionally, the invention provides methods of identifying treatments as well as providing treatments for such an inflammatory response, which include decreasing VEGF or PlGF levels, or increasing sFlt- or PlGF levels.
Endocan Compositions And Methods For The Treatment Of Neoplasms
US Patent:
2006008, Apr 20, 2006
Filed:
Jan 22, 2004
Appl. No.:
10/542717
Inventors:
William Aird - Brookline MA, US
Xianjin Yi - Quincy MA, US
Xianjin Yi - Quincy MA, US
International Classification:
C12Q 1/68, G01N 33/574
US Classification:
435006000, 435007230
Abstract:
The present invention features improved diagnostic and therapeutic methods for neoplasia treatment relating to endocan nucleic acid molecules and polypeptides. In addition, the invention features methods for monitoring the responsive of a tumor in a patient to therapy; methods for suppressing the growth of a neoplasm by inhibiting endocan expression or biological activity; methods for generating a promoter that directs expression of a heterologous nucleic acid sequence specifically to the endothelium of tumor blood vessels; and methods for using such promoters to deliver peptides to a tumor in a patient.