DR. WILLIAM A FRIEDMAN, MD
Medical Practice at Archer Rd, Gainesville, FL

5954647, Sep 21, 1999

Apr 26, 1996

8/638088

Frank J. Bova - Gainesville FL
William A. Friedman - Gainesville FL

University of Florida Research Foundation, Inc. - Gainesville FL

A61B 1900

600407

Repeat fixation for medical procedures is accomplished using a non-invasive locator, specifically a bite plate. The bite plate has at least three fiducial markers on it. The fiducial markers may be LEDs, radiopaque markers for angiography or computerized tomography (CT) imaging or magnetic resonance markers for magnetic resonance (MR) imaging. By detecting the position of the markers, the position of features within the patient (such as a brain tumor or other intracranial target to which radiation is to be applied) can be determined with great precision. Since the bite plate has been molded to uniquely fit to the patient's teeth, it may be removed after an initial imaging of the patient. The bite plate may then be re-attached one or more times to the teeth. An alternate embodiment uses a head ring or head holder such as a head mask system with the LEDs thereon.

6390982, May 21, 2002

Jul 21, 2000

09/621868

Frank M. Bova - Gainesville FL 32607
William A. Friedman - Gainesville FL 32607
Sanford L. Meeks - Iowa City IA 52245
John M. Buatti - Iowa City IA 52240

A16B 0800

600443, 600424, 128916

A system comprising a combination of an ultrasound probe and both passive and active infrared tracking systems. The combined system enables a real time image display of the entire region of interest without probe movement; real time tracking of the target region permitting physiological gating; and probe placement during image acquisition so that all external displacements introduced by the probe can be accounted for at the time of treatment planning. This system may be used in the surgical arena for image guidance during radiation therapy and surgery.

6546279, Apr 8, 2003

Oct 12, 2001

09/975200

Frank J. Bova - Gainesville FL
William A. Friedman - Gainesville FL

University of Florida - Gainesville FL

A61B 505

600429, 600410, 600411, 600417, 600424, 600428, 600434, 600437, 600439, 606130

A computer controlled system for guiding the needle device, such as a biopsy needle, by reference to a single mode medical imaging system employing any one of computed tomography imaging (CTI) equipment, magnetic resonance imaging equipment (MRI), fluoroscopic imaging equipment, or 3D ultrasound system, or alternatively, by reference to a multi-modal imaging system, which includes any combination of the aforementioned systems. The 3D ultrasound system includes a combination of an ultrasound probe and both passive and active infrared tracking systems so that the combined system enables a real time image display of the entire region of interest without probe movement.

7024237, Apr 4, 2006

Oct 29, 1999

09/430034

Frank J. Bova - Gainesville FL, US
William A. Friedman - Gainesville FL, US

University of Florida Research Foundation, Inc. - Gainesville FL

A61B 5/00

600429, 606130

Repeat fixation for medical procedures is accomplished using a non-invasive locator, specifically a face mask. The face mask has at least three fiducial markers on it. By detecting the position of the markers, the position of features within the patient can be determined with great precision. The features can be the location of head or neck cancer or other target to which radiation or other medical procedure is to be applied. Since the face mask has been molded to uniquely fit to the patient's face, it may be removed after an initial imaging of the patient. The face mask may then be re-attached one or more times to the teeth. The face mask is molded to conform to the patient's face by using thermoplastic material.

5189687, Feb 23, 1993

Jun 4, 1991

7/709812

Frank J. Bova - Gainesville FL
William A. Friedman - Gainesville FL

University of Florida Research Foundation, Inc. - Alachua FL

A61N 510

378 65

Stereostactic radiosurgery apparatus for eliminating misalignments due to mechanical inaccuracies and sag of a linear accelerator radiation-emitting head which is swung through an arc comprises a guiding and support structure with a first bearing system for accurately rotating a collimator through a precise arc in a vertical plane with respect to a predetermined center point in the plane corresponding to a treatment location, a second gimbal bearing system for coupling the collimator to the head so that the rotating head can drive the collimator through its arc while mechanically uncoupling the head from the collimator by eliminating torques and forces on the collimator which would be exerted by mechanical inaccuracies or sag of the head, and a third bearing system for rotatably supporting a stereotactic floorstand for rotation about a vertical axis which intersects the center point. Since the movement of the collimator and the rotation of the floorstand are precisely controlled with respect to the center point, the apparatus ensures that radiation from the head will be accurately focused at the center point for all rotational positions of the head and floorstand. Mechanical linking arrangements are shown for allowing the floorstand to rotate automatically upon rotation of a patient treatment table.

5588430, Dec 31, 1996

Feb 14, 1995

8/388024

Frank J. Bova - Gainesville FL
William A. Friedman - Gainesville FL

University of Florida Research Foundation, Inc. - Gainesville FL

A61B 1900

1286531

Repeat fixation for medical procedures is accomplished using a non-invasive locator, specifically a bite plate. The bite plate has at least three fiducial markers on it. The fiducial markers may be LEDs, radiopaque markers for angiography or computerized tomography (CT) imaging or magnetic resonance markers for magnetic resonance (MR) imaging. By detecting the position of the markers, the position of features within the patient (such as a brain tumor or other intracranial target to which radiation is to be applied) can be determined with great precision. Since the bite plate has been molded to uniquely fit to the patient's teeth, it may be removed after an initial imaging of the patient. The bite plate may then be re-attached one or more times to the teeth and the location of the features will be in a known position relative to the sensed markers. The patient's position can then be adjusted in order to bring the features to a desired location, such as bringing an intracranial target to the isocenter of a planned application of radiation.

8099152, Jan 17, 2012

Feb 17, 2006

11/884631

Frank J. Bova - Gainesville FL, US
William A. Friedman - Gainesville FL, US

Univeristy of Florida Research Foundation, Inc. - Gainesville FL

A61B 5/05

600424, 600407, 600425

A method of formulating a patient-specific plan for a diagnostic or therapeutic procedure performed upon a patient is provided. The method includes obtaining a standard plan based upon a scan of an anatomy of a standard anatomic specimen, the scan defining a standard scan. The method also includes scanning the patient to obtain a patient-specific scan of an anatomy of the patient. Additionally, the method includes morphing the standard scan to the anatomy of the patient by mapping the standard scan to the patient-specific scan. The method further includes determining the patient-specific plan by modifying the standard plan based upon the mapping.

2005007, Apr 7, 2005

Oct 2, 2003

10/677419

Frank Bova - Gainesville FL, US
William Friedman - Gainesville FL, US

A61B019/00

606130000

Devices, methods and systems for frameless guidance of image-based medical procedures such as stereotactic radiotherapy and surgery. Devices including custom fitting subject-specific articles include contoured surfaces that provide spatial reference to the location of target regions within the subject. The devices and articles can be fabricated using computer-directed fabrication technology.