WEI MING SUN
Pharmacy in Ann Arbor, MI
License number
Michigan 5315005855
Issued Date
Jun 24, 2001
Expiration Date
Jun 30, 2004
Category
Pharmacy
Type
CS - 1
Address
Address
Ann Arbor, MI 48109
Professional information
Spiro-Oxindole Mdm2 Antagonists
US Patent:
8518984, Aug 27, 2013
Filed:
Nov 12, 2010
Appl. No.:
12/945511
Inventors:
Shaomeng Wang - Saline MI, US
Shanghai Yu - Ann Arbor MI, US
Wei Sun - Ann Arbor MI, US
Sanjeev Kumar - Ann Arbor MI, US
Duxin Sun - Ann Arbor MI, US
Peng Zou - Ann Arbor MI, US
Donna McEachern - Ann Arbor MI, US
Yujun Zhao - Ann Arbor MI, US
Shanghai Yu - Ann Arbor MI, US
Wei Sun - Ann Arbor MI, US
Sanjeev Kumar - Ann Arbor MI, US
Duxin Sun - Ann Arbor MI, US
Peng Zou - Ann Arbor MI, US
Donna McEachern - Ann Arbor MI, US
Yujun Zhao - Ann Arbor MI, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
C07D 487/10, A61K 31/4015
US Classification:
514409, 548406
Abstract:
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.
Spiro-Oxindole Mdm2 Antagonists
US Patent:
8629141, Jan 14, 2014
Filed:
May 11, 2012
Appl. No.:
13/469928
Inventors:
Shaomeng Wang - Saline MI, US
Wei Sun - Ann Arbor MI, US
Angelo Aguilar - Ann Arbor MI, US
Carlos Garcia-Echeverria - Paris, FR
Wei Sun - Ann Arbor MI, US
Angelo Aguilar - Ann Arbor MI, US
Carlos Garcia-Echeverria - Paris, FR
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
Sanofi - Paris
Sanofi - Paris
International Classification:
A61K 31/4015, C07D 209/96, C07D 273/04, C07D 401/14
US Classification:
5142328, 514278, 514409, 544 70, 546 18, 548486
Abstract:
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.
Spiro-Oxindole Mdm2 Antagonists
US Patent:
2012012, May 17, 2012
Filed:
Nov 11, 2011
Appl. No.:
13/294315
Inventors:
Shaomeng Wang - Saline MI, US
Yujun Zhao - Ann Arbor MI, US
Wei Sun - Ann Arbor MI, US
Sanjeev Kumar - Ann Arbor MI, US
Lance Leopold - Dresher PA, US
Laurent Debussche - Paris, FR
Cedric Barriere - Paris, FR
Jean-Christophe Carry - Paris, FR
Kwame Amaning - Paris, FR
Yujun Zhao - Ann Arbor MI, US
Wei Sun - Ann Arbor MI, US
Sanjeev Kumar - Ann Arbor MI, US
Lance Leopold - Dresher PA, US
Laurent Debussche - Paris, FR
Cedric Barriere - Paris, FR
Jean-Christophe Carry - Paris, FR
Kwame Amaning - Paris, FR
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
SANOFI - Paris
ASCENTA THERAPEUTICS, INC. - Malvern PA
SANOFI - Paris
ASCENTA THERAPEUTICS, INC. - Malvern PA
International Classification:
A61K 31/407, A61P 35/00, A61P 35/02, C07D 487/10
US Classification:
514409, 548410
Abstract:
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.