WEI CHEN
Accountancy in Pittsburgh, PA
License number
Pennsylvania CA060811
Category
Accountancy
Type
Certified Public Accountant
Address
Address
Pittsburgh, PA 15238
Professional information
Wei Chen - Havertown, PA
Work:
ADERANS RESEARCH INSTITUTE, INC - Philadelphia, PA
Research Scientist III THOMAS JEFFERSON UNIVERSITY - Philadelphia, PA
Research Associate UNIVERSITY OF PENNSYLVANIA - Philadelphia, PA
Research Fellow NATIONAL INSTITUTE OF HEALTH - Research Triangle Park, NC
Visiting Research Fellow
Research Scientist III THOMAS JEFFERSON UNIVERSITY - Philadelphia, PA
Research Associate UNIVERSITY OF PENNSYLVANIA - Philadelphia, PA
Research Fellow NATIONAL INSTITUTE OF HEALTH - Research Triangle Park, NC
Visiting Research Fellow
Education:
PEKING UNION MEDICAL COLLEGE & CHINESE ACADEMY OF MEDICAL SCIENCES
M.S. in Molecular Immunology and Pharmacology LANZHOU UNIVERSITY - Lanzhou, CHINA
B.S. in Cell Biology
M.S. in Molecular Immunology and Pharmacology LANZHOU UNIVERSITY - Lanzhou, CHINA
B.S. in Cell Biology
Skills:
Apoptosis/cell death, biomarker, stem cell biology, signal transduction, regenerative medicine, neurodegenerative disease, neuroprotection, cell biology, cell culture, cell sorting, cell based assay, ELISA, Flow cytometry, FACS, molecular biology, RT-PCR, realtime PCR, immunology, immunoassay, immunochemistry, ICC, IHC, IFA, FISH, Western blot, microscopy, imaging analysis, microarray, genechip, drug discovery
Graduate Student At Carnegie Mellon University
Location:
Greater Pittsburgh Area
Industry:
Computer Software
Education:
Carnegie Mellon University 2007 - 2009
Biomarkers For Trichogenicity
US Patent:
2010029, Nov 18, 2010
Filed:
Dec 18, 2008
Appl. No.:
12/808623
Inventors:
Satish Parimoo - Bridgewater NJ, US
Honghua Yang - Cherry Hill NJ, US
Ying Homan - Ambler PA, US
Wei Chen - Havertown PA, US
Ying Zheng - West Chester PA, US
Kurt Stenn - Princeton NJ, US
Honghua Yang - Cherry Hill NJ, US
Ying Homan - Ambler PA, US
Wei Chen - Havertown PA, US
Ying Zheng - West Chester PA, US
Kurt Stenn - Princeton NJ, US
International Classification:
C12Q 1/68, G01N 33/566, C12N 15/79
US Classification:
435 6, 435 721, 435375
Abstract:
Biomarkers for identifying trichogenic cells have been identified. The biomarkers include microRNA as wells as mRNA and proteins. Certain biomarkers are upregulated in trichogenic cells compared to non-trichogenic cells; whereas, other biomarkers are down-regulated in trichogenic cells compared to non-trichogenic cells. The cells can be dermal cells, epidermal cells, or a combination thereof. Preferably the cells are mammalian, more preferably the cells are human. One embodiment provides a method for selecting trichogenic cells by assaying the cells for expression of one or more biomarkers for trichogenicity, and selecting the cells having increased expression of the one or more biomarkers relative to a control, wherein increased expression of the a biomarker in the cells is indicative of trichogenicity. Preferably, the one or more biomarkers are selected from the group consisting of hsa-miR-200c, hsa-miR-205, hsa-miR-200a*, hsa-miR-200a, hsa-miR-141, hsa-miR-182, DEPDC1, hFLEG1, ESM1, TOME-1, THBD and combinations thereof.