WARREN STRITTMATTER, M.D.
Neurology at Erwin Rd, Durham, NC
License number
North Carolina 21610
Category
Neurology
Type
Neurology
Address
Address
2100 Erwin Rd, Durham, NC 27710
Phone
(919) 620-4467
Organization information
See more information about WARREN STRITTMATTER at bizstanding.comWarren Strittmatter MD
Dumc, Durham, NC 27710
Industry:
Neurologist
Phone:
(919) 668-5273 (Phone)
Warren James Strittmatter
Professional information
Dr. Warren J Strittmatter, Durham NC - MD (Doctor of Medicine)
Specialties:
Neuropsychiatry (Neurology)
Address:
Duke Movement Disorder Clinic
932 Morreene Rd, Durham 27705
(919) 668-2493 (Phone)
Dumc2900, Durham 27710
932 Morreene Rd, Durham 27705
(919) 668-2493 (Phone)
Dumc2900, Durham 27710
Certifications:
Neurology, 1979
Awards:
Healthgrades Honor Roll
Languages:
English, Spanish
Hospitals:
Duke Movement Disorder Clinic
932 Morreene Rd, Durham 27705
Dumc2900, Durham 27710
Duke University Hospital
2301 Erwin Rd, Durham 27710
932 Morreene Rd, Durham 27705
Dumc2900, Durham 27710
Duke University Hospital
2301 Erwin Rd, Durham 27710
Education:
Medical School
Duke University School Of Medicine
Graduated: 1973
Grady Meml Hospital Emory Hospital
Graduated: 1974
Duke Hospital
Graduated: 1977
Duke University School Of Medicine
Graduated: 1973
Grady Meml Hospital Emory Hospital
Graduated: 1974
Duke Hospital
Graduated: 1977
Warren Strittmatter, Durham NC
Specialties:
Neurology
Work:
Durham Va Medical Center
508 Fulton St, Durham, NC 27705
508 Fulton St, Durham, NC 27705
Education:
Duke University(1973)
Kit For Detecting The Apoe4 Allele, And For Diagnosing The Existence Or Risk Of Developing Alzheimer's Disease
US Patent:
5716828, Feb 10, 1998
Filed:
May 15, 1995
Appl. No.:
8/441001
Inventors:
Allen D. Roses - Durham NC
Warren J. Strittmatter - Durham NC
Guy S. Salvesen - Chapel Hill NC
Jan Enghild - Durham NC
Donald E. Schmechel - Durham NC
Warren J. Strittmatter - Durham NC
Guy S. Salvesen - Chapel Hill NC
Jan Enghild - Durham NC
Donald E. Schmechel - Durham NC
Assignee:
Duke University - Durham NC
International Classification:
C12Q 168, G01N 3353
US Classification:
435 6
Abstract:
Methods of diagnosing or prognosing Alzheimer's disease in a subject are disclosed. The methods involve directly or indirectly detecting the presence or absence of an apolipoprotein E type 4 (ApoE4) isoform or DNA encoding ApoE4 in the subject. The presence of ApoE4 indicates the subject is at risk of developing Alzheimer's disease. A novel immunochemical assay for detecting the presence or absence of the Apoliprotein E (ApoE) E4 allele in a subject is also disclosed.
Method Of Binding Material To The .Beta.-Amyloid Peptide
US Patent:
6294340, Sep 25, 2001
Filed:
Oct 21, 1996
Appl. No.:
8/734490
Inventors:
Warren J. Strittmatter - Durham NC
Allen D. Roses - Durham NC
David Huang - Durham NC
Dmitry Y. Goldgaber - Setauket NY
Allen D. Roses - Durham NC
David Huang - Durham NC
Dmitry Y. Goldgaber - Setauket NY
Assignee:
Duke University - Durham NC
International Classification:
G01N 3353, G01N 33543, G01N 33563
US Classification:
435 71
Abstract:
The present invention relates to the finding that antibodies bind to the. beta. -amyloid peptide, and that. beta. -amyloid peptide binds the hinge region of the immunoglobulin heavy chain, thereby preserving the ability of the immunoglobulin to bind antigen. Methods for binding compounds such as detectable groups to. beta. -amyloid peptide are accordingly presented.
Methods Of Detecting Alzheimer's Disease
US Patent:
6027896, Feb 22, 2000
Filed:
Apr 15, 1998
Appl. No.:
9/060459
Inventors:
Allen D. Roses - Durham NC
Warren J. Strittmatter - Durham NC
Guy S. Salvesen - Chapel Hill NC
Jan Enghild - Durham NC
Donald E. Schmechel - Durham NC
Warren J. Strittmatter - Durham NC
Guy S. Salvesen - Chapel Hill NC
Jan Enghild - Durham NC
Donald E. Schmechel - Durham NC
Assignee:
Duke University - Durham NC
International Classification:
C12Q 168, G01N 3353, C12P 1934, C07H 2102
US Classification:
435 6
Abstract:
Methods of diagnosing or prognosing Alzheimer's disease in a subject are disclosed. The methods involve directly or indirectly detecting the presence or absence of an apolipoprotein E type 4 (ApoE4) isoform or DNA encoding ApoE4 in the subject. The presence of ApoE4 indicates the subject is afflicted with Alzheimer's disease or at risk of developing Alzheimer's disease. A novel immunochemical assay for detecting the presence or absence of the Apoliprotein E (ApoE) E4 allele in a subject is also disclosed.
Methods Of Screening For Alzheimer's Disease
US Patent:
5508167, Apr 16, 1996
Filed:
Apr 13, 1994
Appl. No.:
8/227044
Inventors:
Allen D. Roses - Durham NC
Warren J. Strittmatter - Durham NC
Guy S. Salvesen - Chapel Hill NC
Jan Enghild - Durham NC
Donald E. Schmechel - Durham NC
Warren J. Strittmatter - Durham NC
Guy S. Salvesen - Chapel Hill NC
Jan Enghild - Durham NC
Donald E. Schmechel - Durham NC
Assignee:
Duke University - Durham NC
International Classification:
C12Q 168, C12Q 100, C12P 1934
US Classification:
435 6
Abstract:
Methods of diagnosing or prognosing Alzheimer's disease in a subject are disclosed. The methods involve directly or indirectly detecting the presence or absence of an apolipoprotein E type 4 (ApoE4) isoform or DNA, encoding ApoE4 in the subject. The presence of ApoE4 indicates the subject is afflicted with Alzheimer's disease or at risk of developing Alzheimer's disease. A novel immunochemical assay for detecting the presence or absence of the Apoliprotein E (ApoE) E4 allele in a subject is also disclosed.
Compounds That Selectively Bind To Expanded Polyglutamine Repeat Domains And Methods Of Use Thereof
US Patent:
2003022, Dec 11, 2003
Filed:
Apr 14, 2003
Appl. No.:
10/413160
Inventors:
James Burke - Chapel Hill NC, US
Warren Strittmatter - Durham NC, US
Yoshitaka Nagai - Osaka, JP
Warren Strittmatter - Durham NC, US
Yoshitaka Nagai - Osaka, JP
International Classification:
A61K038/16, A61K048/00, G01N033/53, C07H021/04, C12P021/02, C12N005/06, C07K014/47
US Classification:
514/012000, 514/044000, 435/007100, 435/069100, 435/320100, 435/325000, 530/324000, 536/023100
Abstract:
Compounds that selectively bind to expanded polyglutamine repeats are disclosed. Such compounds are characterized in that they bind to a first polyglutamine peptide consisting of 60 glutamine residues under conditions in which they do not bind to a second polyglutamine peptide consisting of 20 glutamine residues. Conjugates of such compounds, nucleic acids encoding the same, and methods of use thereof are also disclosed.
Method To Screen Compounds That Affect Gapdh Binding To Polyglutamine
US Patent:
5723301, Mar 3, 1998
Filed:
Nov 3, 1995
Appl. No.:
8/553110
Inventors:
James R. Burke - Chapel Hill NC
Jeffery M. Vance - Durham NC
Jan Enghild - Durham NC
Warren J. Strittmatter - Durham NC
Jeffery M. Vance - Durham NC
Jan Enghild - Durham NC
Warren J. Strittmatter - Durham NC
Assignee:
Duke University - Durham NC
International Classification:
G01N 3368
US Classification:
435 71
Abstract:
GAPDH binds to expanded polyglutamine regions which are found in proteins encoded by genes with CAG repeat domains, which genes cause inherited neurodegenerative disorders and are associated with certain psychiatric disorders. Therapeutic methods are based on inhibiting the binding of GAPDH to expanded polyglutamine regions. A method of screening compounds for the ability to inhibit binding of GAPDH to polyglutamine regions is described.
Apolipoprotein E Isoform-Specific Monoclonal Antibodies
US Patent:
5767248, Jun 16, 1998
Filed:
Apr 8, 1997
Appl. No.:
8/835503
Inventors:
Allen D. Roses - Durham NC
Warren J. Strittmatter - Durham NC
Guy S. Salvesen - Chapel Hill NC
Jan Enghild - Durham NC
Donald E. Schmechel - Durham NC
Warren J. Strittmatter - Durham NC
Guy S. Salvesen - Chapel Hill NC
Jan Enghild - Durham NC
Donald E. Schmechel - Durham NC
Assignee:
Duke University - Durham NC
International Classification:
C07K 1600
US Classification:
53038825
Abstract:
Methods of diagnosing or prognosing Alzheimer's disease in a subject are disclosed. The methods involve directly or indirectly detecting the presence or absence of an apolipoprotein E type 4 (ApoE4) isoform or DNA encoding ApoE4 in the subject. The presence of ApoE4 indicates the subject is afflicted with Alzheimer's disease or at risk of developing Alzheimer's disease. A novel immunochemical assay for detecting the presence or absence of the Apoliprotein E (ApoE) E4 allele in a subject is also disclosed.
Source Of Apolipoprotein E And Method Of Isolating Apolipoprotein E
US Patent:
5672685, Sep 30, 1997
Filed:
Oct 4, 1995
Appl. No.:
8/539328
Inventors:
William D. Matthew - Durham NC
Warren J. Strittmatter - Durham NC
Catherine R. Gutman - Durham NC
Warren J. Strittmatter - Durham NC
Catherine R. Gutman - Durham NC
Assignee:
Duke University - Durham NC
International Classification:
C07K 122, C07K 1447, C07K 14775
US Classification:
530359
Abstract:
Peritoneal fluid and peritoneal wash fluid provide a source of abundant apolipoprotein E. Methods for isolating apolipoprotein E from peritoneal fluid or peritoneal wash fluid are provided.