Inventors:
Ron S. Israeli - Staten Island NY, US
Warren D.W. Heston - Cleveland OH, US
William R. Fair - Longboat FL, US
Maryann Fair - Longboat FL, US
International Classification:
A61K 51/00, C12N 5/07, C12N 5/09, A61K 39/395, G01N 33/567, A61K 49/00, C07K 16/28, C12N 9/96, C12N 5/10, A61P 35/00
US Classification:
424 111, 435375, 4241721, 435 721, 424 91, 5303891, 5303882, 5303917, 5303913, 435188, 435332
Abstract:
This invention provides an isolated mammalian nucleic acid molecule encoding an alternatively spliced prostate-specific membrane (PSM′) antigen.This invention provides an isolated nucleic acid molecule encoding a prostate-specific membrane antigen promoter. This invention provides a method of detecting hematogenous micrometastic tumor cells of a subject, and determining prostate cancer progression in a subject.