Inventors:
Gilbert Chu - Palo Alto CA, US
Virginia Tusher - Belvedere CA, US
Jean Tang - Stanford CA, US
Kerri Rieger - Menlo Park CA, US
Wan-Jen Hong - Palo Alto CA, US
Robert Tibshirani - Stanford CA, US
International Classification:
C12Q001/68
Abstract:
Methods are provided for determining whether a patient treated with an anti-proliferative agent is susceptible to toxicity. In practicing the subject methods, an expression profile for the transcriptional response to a therapy is obtained from the patient and compared to a reference profile to determine whether the patient is susceptible to toxicity. In addition, reagents and kits thereof that find use in practicing the subject methods are provided.