Inventors:
Vivian S. Lee - Salt Lake City UT, US
Henry Rusinek - Great Neck NY, US
Lei Zhang - Salt Lake City UT, US
Assignee:
New York University - New York NY
International Classification:
A61B 5/055, A61B 6/00
Abstract:
Exemplary embodiments of method, system and computer-accessible medium according to the present disclosure can be provided for converting magnetic resonance (MR) arterial signal intensity versus time curves to arterial input functions (AIF) with less susceptibility to artifacts such as flow-related enhancement. Exemplary methods, systems and computer-accessible medium can be used to constrain AIF to satisfies the indicator dilution principle, according to which the area under an initial pass component of AIF can be equal to the injected dose divided by the cardiac output. For example, Monte Carlo simulations of MR renography and tumor perfusion protocols can be performed for comparison with conventional methods.