VIRGINIA LEE
Nursing in Philadelphia, PA
License number
Pennsylvania PN025400L
Category
Nursing
Type
Practical Nurse
Address
Address
Philadelphia, PA 19138
Personal information
See more information about VIRGINIA LEE at radaris.comName
Address
Phone
445 High St, Brownsville, PA 15417
Organization information
See more information about VIRGINIA LEE at bizstanding.comACME VIRGINIA LEE
Philadelphia, PA
Status:
Inactive
Registration:
Feb 21, 1962
State ID:
72138364
Reg. number:
0749486
Status:
900 - Expired
Status date:
Oct 14, 1987
Illustration:
Drawing or design which also includes word(s)/ letter(s)/number(s)
Goods & Services:
As early as march 1935 as to "virginia lee" on bakery foods, As early as march 1935 as to "virginia lee" on bakery foods, Breads, pastries, donuts, cookies, cakes, pies, pretzels, potato chips, icecre...
Owner:
124 N 15 St, Philadelphia, PA
Professional information
Administration Of An Agent Which Decreases Processing Of Amyloid Precursor Protein
US Patent:
2003018, Oct 2, 2003
Filed:
Jun 28, 1999
Appl. No.:
09/297877
Inventors:
VIRGINIA M.-Y. LEE - PHILADELPHIA PA, US
ROBERT W. DOMS - BERWYN PA, US
ROBERT W. DOMS - BERWYN PA, US
International Classification:
G01N033/53
US Classification:
435/007100
Abstract:
secretase pathways which process amyloid precursor protein into the amyloid peptides of neuritic plaques and vascular deposits that accumulate in the brains of patients with Alzheimer's disease have been identified in the endoplasmic reticulum of neuronal cells. Methods of identifying compounds which increase or decrease processing of amyloid precursor protein via these pathways which may be useful in the treatment of Alzheimer's disease and in identifying causative agents of this disease are provided.
Method Of Screening For Alzheimer's Disease Or Disease Associated With The Accumulation Of Paired Helical Filaments
US Patent:
5733734, Mar 31, 1998
Filed:
Oct 29, 1993
Appl. No.:
8/145827
Inventors:
John Q. Trojanowski - Philadelphia PA
Virginia M-Y. Lee - Philadelphia PA
Virginia M-Y. Lee - Philadelphia PA
Assignee:
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
G01N 3353, C07K 1618
US Classification:
435 71
Abstract:
Substantially purified antibodies, including substantially purified monoclonal antibodies, which are specifically reactive with. tau. that has an abnormally phosphorylated serine in the sequence LysSerProVal SEQ ID NO:3 are disclosed. Methods of screening persons for diseases associated with pair helical filaments, including Alzheimer's disease, by detection of. tau. that has an abnormally phosphorylated serine in the sequence LysSerProVal SEQ ID NO:3 in test samples taken from such persons and test kits useful to perform such methods are disclosed.
Compositions And Methods For Producing And Using Homogenous Neuronal Cell Transplants
US Patent:
2006002, Feb 9, 2006
Filed:
Sep 29, 2005
Appl. No.:
11/242114
Inventors:
Virginia Lee - Philadelphia PA, US
John Trojanowski - Philadelphia PA, US
John Trojanowski - Philadelphia PA, US
International Classification:
A61K 45/00, C12N 5/08
US Classification:
424093100, 435368000
Abstract:
Methods of treating individuals suspected of suffering from diseases, conditions or disorders of the Central Nervous System which comprise implanting stable, homogeneous post-mitotic human neurons into the individual's brain are disclosed. Methods of treating individuals suspected of suffering from injuries, diseases, conditions or disorders characterized by nerve damage which comprise implanting stable, homogeneous post-mitotic human neurons at or near a site of said nerve damage. Pharmaceutical compositions comprising stable, homogeneous post-mitotic human neurons and a pharmaceutically acceptable medium are disclosed. Methods of generating non-human animal models of human CNS diseases, conditions or disorders which comprise implanting stable, homogeneous post-mitotic human neurons into the brain of a non-human animal are disclosed. Non-human animals comprising stable, homogeneous post-mitotic human neurons implanted in their brain are disclosed.
Novel Tetrahydronaphalene Antagonists To The Thromboxane A2 (Tp) Receptor
US Patent:
2013019, Jul 25, 2013
Filed:
Jul 27, 2011
Appl. No.:
13/812793
Inventors:
John Q. Trojanowski - Philadelphia PA, US
Virginia M.Y. Lee - Philadelphia PA, US
Kurt R. Brunden - Medla PA, US
Amos B. Smith - Merion PA, US
Donna M. Huryn - Allentown NJ, US
Carlo Ballatore - Philadelphia PA, US
Anne-Marie Hogan - Mount Merrion, IE
Francesco Piscitelli - Marina dl Strongoii, IT
Virginia M.Y. Lee - Philadelphia PA, US
Kurt R. Brunden - Medla PA, US
Amos B. Smith - Merion PA, US
Donna M. Huryn - Allentown NJ, US
Carlo Ballatore - Philadelphia PA, US
Anne-Marie Hogan - Mount Merrion, IE
Francesco Piscitelli - Marina dl Strongoii, IT
Assignee:
The Trustees of the University of Pennsylvania - Philadephia PA
International Classification:
C07C 311/20, C07D 317/28, A61K 31/196, A61K 45/06, A61K 31/18, A61K 31/41, A61K 31/357, C07D 257/04, A61K 31/216
US Classification:
514381, 560 10, 562430, 564 91, 548252, 549491, 514510, 514562, 514604, 514467
Abstract:
The present invention relates to TP receptor antagonists, which have the ability to bind to TP receptor and optionally cross the blood brain barrier. The invention also provides compositions and methods for treating a disorder wherein activation of TP receptor is detrimental.
Preparation Of Pure Cultures Of Post-Mitotic Human Neurons
US Patent:
5175103, Dec 29, 1992
Filed:
Oct 21, 1991
Appl. No.:
7/780715
Inventors:
Virginia Lee - Philadelphia PA
Samuel Pleasure - Philadelphia PA
Samuel Pleasure - Philadelphia PA
Assignee:
Trustees of University of Pennsylvania - Philadelphia PA
International Classification:
C12N 508, C12N 510
US Classification:
4351723
Abstract:
NTera 2/cl. D1 (NT2) cells, a human teratocarcinoma cell line, were manipulated following retinoic acid (RA) treatment to yield>95% pure cultures of neuronal cells (NT2-N cells). This culture method is capable of yielding sufficient highly differentiated post-mitotic NT2-N cells for both biochemical and molecular biological studies. NT2 cells can be transfected efficiently and the transfected gene products can be expressed in both NT2 and NT2-N cells.
Transgenic Animal Expressing Alpha-Synuclein And Uses Thereof
US Patent:
2003021, Nov 20, 2003
Filed:
May 16, 2002
Appl. No.:
10/150043
Inventors:
Benoit Giasson - Lansdowne PA, US
John Trojanowski - Philadelphia PA, US
Virginia Lee - Philadelphia PA, US
John Trojanowski - Philadelphia PA, US
Virginia Lee - Philadelphia PA, US
International Classification:
A01K067/00
US Classification:
800/003000, 800/008000
Abstract:
The present invention relates to transgenic animals expressing A53T -Syn protein which are models for neurodegenerative disease progression. These animals may be used for screening candidate drug compounds effective against neurodegenerative diseases and other diseases involving -synucleinopathy.
Compositions And Methods For Producing And Using Homogenous Neuronal Cell Transplants
US Patent:
5792900, Aug 11, 1998
Filed:
Jun 7, 1996
Appl. No.:
8/640894
Inventors:
Virginia M.-Y. Lee - Philadelphia PA
John Q. Trojanowski - Philadelphia PA
John Q. Trojanowski - Philadelphia PA
Assignee:
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
C12N 1500, C12N 506
US Classification:
800 2
Abstract:
The invention concerns populations of homogenous, post-mitotic human NT2N neurons that are useful for generating animal systems for study of neuron function. Also disclosed are methods of preparing animals that are useful for study of neurological function. In these methods, differentiated NT2N cells are stably implanted into host rodent animals.
Detection Of Neurodegenerative Disease
US Patent:
2009026, Oct 22, 2009
Filed:
Mar 26, 2009
Appl. No.:
12/412015
Inventors:
Virginia M.Y. Lee - Philadelphia PA, US
John Q. Trojanowski - Philadelphia PA, US
John Q. Trojanowski - Philadelphia PA, US
Assignee:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA - Philadelphia PA
International Classification:
G01N 33/53, C07K 16/00
US Classification:
435 71, 5303871
Abstract:
Provided are methods of assessing the absence or presence of a neurodegenerative disease in a subject comprising characterizing TDP-43 in a tissue sample of the subject. Also disclosed are methods for diagnosing a neurodegenerative disease in a subject, and methods for determining the efficacy of a drug against a neurodegenerative disease. Novel antibodies that bind to TDP-43 are also provided.
Rat Comprising Straight Filaments In Its Brain
US Patent:
5849988, Dec 15, 1998
Filed:
Jun 17, 1994
Appl. No.:
8/261810
Inventors:
John Q. Trojanowski - Philadelphia PA
Virginia M.-Y. Lee - Philadelphia PA
Ryong-Woon Shin - Fukuoka, JP
Virginia M.-Y. Lee - Philadelphia PA
Ryong-Woon Shin - Fukuoka, JP
Assignee:
Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
C12N 500, C12N 1500, A61K 4900, A61K 3800
US Classification:
800 2
Abstract:
Methods of generating a rat having A. beta. deposits in the brain of the rat by injecting an amount of human A68 protein sufficient to result in formation of the deposits and subsequently examining the rat for the formation of the deposits are disclosed. Rats characterized by the presence of A. beta. deposits similar to those found in individuals with Alzheimer's disease are also disclosed. Methods of screening test compositions for prophylactic or therapeutic activity by generating a rat having A. beta. deposits in its brain, treating the animal with the test composition and examining the animal for therapeutic or prophylactic effectiveness are also disclosed.
Cell-Based Models Of Neurodegenerative Disease
US Patent:
2013033, Dec 19, 2013
Filed:
Nov 4, 2011
Appl. No.:
13/882674
Inventors:
Kurt R. Brunden - Media PA, US
Virginia M.Y. Lee - Philadelphia PA, US
John Q. Trojanowski - Philadelphia PA, US
Kelvin C. Luk - Philadelphia PA, US
Jing Guo - Philadelphia PA, US
Virginia M.Y. Lee - Philadelphia PA, US
John Q. Trojanowski - Philadelphia PA, US
Kelvin C. Luk - Philadelphia PA, US
Jing Guo - Philadelphia PA, US
Assignee:
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
G01N 33/68, G01N 33/50
US Classification:
435 613, 435325, 435 29
Abstract:
The present invention relates to a cell-based model useful for identifying molecules that modify intracellular pathways of α-synuclein and tau aggregation and degradation.