VIKRAM KATRAGADDA
Pharmacy in Trenton, NJ
License number
Michigan 5302037858
Issued Date
May 8, 2007
Expiration Date
Jun 30, 2010
Category
Pharmacy
Type
Pharmacist - Ed Ltd
Address
Address
Trenton, NJ 08648
Professional information
Composition Of Rapid Disintegrating Direct Compression Buccal Tablet
US Patent:
2009026, Oct 22, 2009
Filed:
Apr 14, 2009
Appl. No.:
12/423552
Inventors:
Vikram Katragadda - Lawrenceville NJ, US
International Classification:
A61K 9/48, A61K 9/20, A61K 31/485
US Classification:
424452, 424465, 514282
Abstract:
A composition of a rapidly disintegrating buccal dosage form containing a drug, at least one non-effervescent base such as an alkali metal or alkaline earth metal oxide or hydroxide, and a disintegrant. The base regulates the pH gradient to deliver the drug to the buccal, sublingual or oral mucosal membranes at a desired rate of absorption. The composition is micronized for uniform distribution, and the drug is converted from ionized form to unionized form, without the use of an effervescent agent.