DR. VICTORIO CAJIGAL RODRIGUEZ, M.D.
Ambulatory Health at 55 St, Cleveland, OH

6821997, Nov 23, 2004

Feb 15, 2002

10/077719

Victorio C. Rodriguez - Parma OH 44134

A61K 31417

514400, 514396, 514397, 514398, 514399, 514878, 514879

A method for the treatment and prophylaxis of conditions of aging in humans, such conditions of aging associated with a decreased presence of cell-specific carbonic anhydrase enzymes in the brain, such as conditions associated with chronic neurodegenerative conditions including dementia such as Alzheimers disease, which method includes the administering over an extended period of time, ranging from 6 months to 5 years, of a pharmaceutically effective, non-toxic amount of a compound that increases the presence of cell-specific carbonic anhydrase enzymes in the brain. That compound may be the cell-specific carbonic anhydrase enzyme, a compound that when absorbed by the body reacts or dissociates to form the cell-specific carbonic anhydrase enzyme, or a compound that promotes the natural generation of the cell-specific carbonic anhydrase enzyme within the body.

2010013, Jun 3, 2010

Jan 7, 2010

12/655783

Victorio C. Rodriguez - Parma OH, US

A61K 38/51, A61P 35/00, A61P 19/08, A61P 19/02, A61P 37/00, A61P 25/00, A61P 17/00

424 945

A method for the treatment and prophylaxis of diseases or conditions associated with aging which includes oxidative stress and cancer. Such diseases or conditions are associated with a decrease or increase presence of one or a combination of one or more Carbonic Anhydrase isozymes I TO VII in the tissue of a subject. These diseases include but are not limited to chronic neurodegenerative diseases such as Alzheimer's disease, parkinson's disease, multiple sclerosis, autism, lou gehrig's disease, huntington's disease, immune disorders which includes systemic lupus erythematosus, diabetes mellitus; musculo-skeletal disorders which includes osteoporosis,arthritis, osteomalacia. Cancer which includes the breast, lung, colon, prostate gland, ovary, esophagus, liver, rectum. The method comprises administering to the patient a pharmaceutically effective non toxic amount of one or a combination of one or more compounds that increases or decreases the level of one or more Cell Specific Carbonic Anhydrase Enzymes whose levels have been increased or decreased in the tissue of the subject. Such compound maybe the Cell Specific Carbonic Anhydrase Enzymes I to VII. A compound that when absorbed reacts or dissociates to form cell specific carbonic enzymes or one or more compounds that when administered promotes the increase or decrease level of one or more cell specific Carbonic anhydrase I,II,III,IV,V,VI,VII. As growth factors of stem cells as an alternative to stem cell therapy. These methods includes the administering of one or a combination of one or more of these compounds over an extended period of time ranging from 6 months until the patient dies.

7858602, Dec 28, 2010

May 12, 2007

11/801870

Victorio C. Rodriguez - Parma OH, US

A61K 31/593, A61K 33/30, A61K 31/315, A61K 31/405, A61K 31/23, A61K 31/145, A61P 25/28

514167, 514168, 514420, 514494, 514548, 514665, 514879, 424641, 424643

A method for the treatment and prophylaxis of conditions of aging due oxidative stress and as growth factors of stem cells. Such conditions due to oxidative stress are associated with a decreased presence of one or more cell-specific carbonic anhydrase enzymes in the tissue of a subject. Such conditions include but are not limited to alzheimer's disease, parkinson's disease, multiple sclerosis, autism, lou gehrig's disease, huntington's disease, diabetes mellitus, amyloid diseases, atherosclerosis, arthritis, osteoporosis, cystic fibrosis. The method comprises administering to the patient a pharmaceutically effective, non-toxic amount of one or more compounds that increases the presence of one or more Carbonic Anhydrase Isozymes whose levels have been reduced in the subject. Such compound maybe the Cell Specific Carbonic Anhydrase Enzymes, a compound that when absorbed reacts or dissociates to form cell specific carbonic enzymes or a compound that when administered promotes the natural generation of the cell specific carbonic anhydrase enzymes within the subject. This method also uses one or more cells specific carbonic anhydrase as growth factors of stem cells for replacing tissues due to injuries or diseases in humans.

5944021, Aug 31, 1999

Feb 13, 1998

9/023062

Victorio C. Rodriguez - Parma OH

A61B 1900

128898

A method for treating victims of cerebral edema is presented that includes the intravenous injection of a carbonic anhydrase enzyme inhibitor that passes through the blood-brain barrier, such as acetazolamide (A. K. A. , DIAMOX. RTM. ), which is a readily-available and often-prescribed diuretic. Such edema, or brain swelling may be caused as a result of ischemic strokes especially, but also swelling due to tumors, surgeries, or cerebral trauma. It is preferred to combine the a carbonic anhydrase enzyme inhibitor therapy with hyperventilation of the lungs, even including the use of supplemental oxygen, thereby to reduce the concentration of carbon dioxide in the blood and hence in the brain.

5411493, May 2, 1995

Sep 27, 1993

8/126928

Victorio C. Rodriguez - Parma OH

A61M 3500

604290

A method for treating hypothermia or hyperthermia patients is presented wherein the upper torso of the patient is maintained in close contact with a wet absorbent material in a vestlike garment that carries a water supply to maintain the absorbent material wet to effect sensible heat transfer between the patient and the water. In one embodiment, evaporative cooling is moderated by an overgarment of a waterproof material.

5411494, May 2, 1995

Sep 27, 1993

8/126929

Victorio C. Rodriguez - Parma OH

A61M 3500

604290

A therapeutic method for treating hypothermia and hyperthermia conditions in human patients by applying a continuous flow of temperature-controlled warmed water over a substantial area of the body of the patient to effect sensible heat transfer between the body and the water. Apparatus is provided for warming, delivering, and distributing the water flow over at least fifty percent of the patient's body and for collecting spent water into a receptacle. A network of water-permeable tubes delivers a flow of warmed water to an absorbent web draped over the body of the patient, thereby to distribute the water flow over a large area and in close proximity to and wetting the surface of the patient's body, thereby to effect sensible heat transfer over a large area. Evaporative heat loss may be minimized by reducing air convection adjacent the water flow.

5755237, May 26, 1998

Jun 7, 1995

8/490110

Victorio C. Rodriguez - Parma OH

A61B 1900

128898

A method for treating victims of cerebral edema is presented that includes the intravenous injection of acetazolamide (A. K. A. , DIAMOX. RTM. ), which is a readily-available and often-prescribed diuretic. Such edema, or brain swelling may be caused as a result of ischemic strokes especially, but also swelling due to tumors, surgeries, or cerebral trauma. It is preferred to combine the acetazolamide therapy with hyperventilation of the lungs, even including the use of supplemental oxygen, thereby to reduce the concentration of carbon dioxide in the blood and hence in the brain.

7256184, Aug 14, 2007

Jun 1, 2004

10/858091

Victorio C. Rodriguez - Parma OH, US

A61K 31/593, A61P 25/00, A61P 25/18, A61P 25/24, A61P 25/28

514167, 514878, 514879, 514903

A method for the treatment and prophylaxis of conditions of aging in humans, such conditions of aging associated with a decreased presence of one or more cell-specific carbonic anhydrase enzymes. Such conditions include chronic neurodegenerative conditions including dementia such as Alzheimer's disease. The method comprises administering to the patient a pharmaceutically effective, non-toxic amount of a compound that increases the presence of one or more cell-specific carbonic anhydrase enzymes whose levels are reduced in the patient. Such compound may be the cell-specific carbonic anhydrase enzyme, a compound that when absorbed by the body reacts or dissociates to form the cell-specific carbonic anhydrase enzyme, or a compound that promotes the natural generation of the cell-specific carbonic anhydrase enzyme within the body.

5570477, Nov 5, 1996

Jun 15, 1995

8/490956

Victorio C. Rodriguez - Parma OH

E03D 9052

4213

A portable fan apparatus is provided for ventilating toilet bowls by forced ventilation wherein air from the toilet bowl is exhausted by the fan via a tube that extends through the water trap formed by water in the trap formed partly by the bottom of the toilet bowl and partly by the drain portion of the toilet, thereby exhausting the foul air into the drain line of the building's plumbing system. The apparatus can be carried by a traveler from toilet to toilet, thereby to provide the desired ventilation for any toilet facility the traveler may visit.