Inventors:
James Eberwine - Philadelphia PA, US
Tai Kyung Kim - Wynnewood PA, US
Vickas Patel - Berwyn PA, US
International Classification:
C12N 15/85, C12N 5/071, C12N 1/20, C12N 15/63
US Classification:
435455, 435471, 435375, 435377, 4352521, 435366
Abstract:
The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome.