VENKATA R GARIGAPATI
Pharmacy in Southborough, MA
License number
Massachusetts RPH03775
Issued Date
8, 1995
Expiration Date
6, 1996
Category
Pharmacy
Type
Pharmacist
Address
Address
Southborough, MA
Education
ANDHRA U/INDIA, May 9, 1981
Professional information
Protein Stabilization Formulations
US Patent:
8435943, May 7, 2013
Filed:
Apr 19, 2011
Appl. No.:
13/089683
Inventors:
Venkata R. Garigapati - Southborough MA, US
Dongling Su - Franklin MA, US
Rehan Khanzada - Middleborough MA, US
Steven J. Sawamura - Newark CA, US
Dongling Su - Franklin MA, US
Rehan Khanzada - Middleborough MA, US
Steven J. Sawamura - Newark CA, US
Assignee:
Advanced Technogies and Regenerative Medicine, LLC - Raynham MA
International Classification:
A61K 38/00, A61K 38/16, A61K 38/17, A61K 38/18
US Classification:
514 76, 514 88, 514 89, 514 167, 514 168, 514 169, 514 171, 514 172, 424422, 424423
Abstract:
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including trehalose as an excipient for lyophilized compositions and their subsequent storage and reconstitution, and can also optionally include other excipients, including buffers and surfactants.
Protein Formulations For Use At Elevated Temperatures
US Patent:
7964561, Jun 21, 2011
Filed:
Jan 28, 2010
Appl. No.:
12/695357
Inventors:
Venkata Garigapati - Southborough MA, US
Dongling Su - Dorchester MA, US
Julius Lopez - Dorchester MA, US
Dongling Su - Dorchester MA, US
Julius Lopez - Dorchester MA, US
Assignee:
Advanced Technologies and Regenerative Medicine, LLC - Raynham MA
International Classification:
A61K 38/16, A61K 38/17, A61K 38/18, C07H 1/00
US Classification:
514 89, 514 88, 514 76, 514 167, 514 168, 514 169, 514 171, 5361231
Abstract:
Liquid formulations of bone morphogenetic proteins are provided for prolonged use at elevated temperatures. More specifically, the invention relates to liquid formulations comprising rhGDF-5, trehalose, and one or more biocompatible excipients that provide stability to the protein for at least 30 days at temperatures up to body temperature.
Protein Stabilization Formulations
US Patent:
7956028, Jun 7, 2011
Filed:
Dec 4, 2007
Appl. No.:
11/950127
Inventors:
Venkata R. Garigapati - Southborough MA, US
Dongling Su - Franklin MA, US
Rehan Khanzada - Middleborough MA, US
Steven J. Sawamura - Newark CA, US
Dongling Su - Franklin MA, US
Rehan Khanzada - Middleborough MA, US
Steven J. Sawamura - Newark CA, US
Assignee:
Johnson & Johnson Regenerative Therapeutics, LLC - Raynham MA
International Classification:
A61K 38/00, A61K 38/16, A61K 38/17, A61K 38/18, C07K 14/00, C07K 14/435, C07K 14/46, C07K 14/47, C07K 14/475, C07K 14/51
US Classification:
514 2, 514 7, 514 8, 530350, 530395, 530399
Abstract:
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including trehalose as an excipient for lyophilized compositions and their subsequent storage and reconstitution, and can also optionally include other excipients, including buffers and surfactants.
Protein Formulations For Use At Elevated Temperatures
US Patent:
7678764, Mar 16, 2010
Filed:
Jun 24, 2008
Appl. No.:
12/145016
Inventors:
Venkata Garigapati - Southborough MA, US
Dongling Su - Franklin MA, US
Julius Lopez - Dorchester MA, US
Dongling Su - Franklin MA, US
Julius Lopez - Dorchester MA, US
Assignee:
Johnson & Johnson Regenerative Therapeutics, LLC - Raynham MA
International Classification:
A61K 38/16, A61K 38/17, A61K 38/18, A61K 38/19, A61K 31/195, A61K 31/198, A61K 31/205
US Classification:
514 2, 514 7, 514 8, 514 12, 514 54, 514 77, 536 111
Abstract:
Liquid formulations of bone morphogenetic proteins are provided for prolonged use at elevated temperatures. More specifically, the invention relates to liquid formulations comprising rhGDF-5, trehalose, and one or more biocompatible excipients that provide stability to the protein for at least 30 days at temperatures up to body temperature.