Inventors:
Giang Au - Sicklerville NJ, US
Ari D. Brooks - Cherry Hill NJ, US
Vanlila K. Swami - Philadelphia PA, US
Assignee:
PHILADELPHIA HEALTH & EDUCATION CORPORATION - PHILADELPHIA PA
DREXEL UNIVERSITY - PHILADELPHIA PA
International Classification:
G01N 33/574
Abstract:
One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an enhanced detection sensitivity and selectivity and may be formed using a novel and efficient method for conjugating one or more biomarker specific moieties to the quantum dots. The invention is further directed to a method for using the conjugated quantum dots for cancer detection in the margin of excised tissue.