VALENTINA KON, MD
Medical Practice in Nashville, TN
License number
Tennessee MD17391
Category
Medical Practice
Type
Pediatric Nephrology
Address
Address
3601 Tvc, Nashville, TN 37232
Phone
(615) 322-3000
Organization information
See more information about VALENTINA KON at bizstanding.comValentina Kon MD
1161 21 Ave S, Nashville, TN 37232
Industry:
Pediatric Kidney Care, Pediatrician, Internist
Phone:
(615) 322-7416 (Phone)
Description:
There are 5 doctors at this site. Surgery is not performed at this site.
Valentina Kon
Professional information
Valentina Kon, Nashville TN
Specialties:
Internal Medicine, Nephrology, Pediatrics, Pediatric Nephrology
Work:
Vanderbilt Pediatric Urology
3601 The Vanderbilt Clinic, Nashville, TN 37232
3601 The Vanderbilt Clinic, Nashville, TN 37232
Education:
Yeshiva University (1977)
Dr. Valentina Kon - MD (Doctor of Medicine)
Hospitals:
Vanderbilt University PNE
1161 21St Ave S STE C4204, Nashville 37232
2200 Childrens Way, Nashville 37232
Vanderbilt University Hospital
1211 Medical Center Dr, Nashville 37232
Vanderbilt University PNE
1161 21St Ave S STE C4204, Nashville 37232
2200 Childrens Way, Nashville 37232
Vanderbilt University Hospital
1211 Medical Center Dr, Nashville 37232
1161 21St Ave S STE C4204, Nashville 37232
2200 Childrens Way, Nashville 37232
Vanderbilt University Hospital
1211 Medical Center Dr, Nashville 37232
Vanderbilt University PNE
1161 21St Ave S STE C4204, Nashville 37232
2200 Childrens Way, Nashville 37232
Vanderbilt University Hospital
1211 Medical Center Dr, Nashville 37232
Education:
Medical Schools
Albert Einstein College Of Medicine Of Yeshiva University
Graduated: 1977
Albert Einstein College Of Medicine Of Yeshiva University
Graduated: 1977
Method And Compositions For Maintaining Glomerular Filtration Rate While Inhibiting Extracellular Matrix Accumulation
US Patent:
6531482, Mar 11, 2003
Filed:
Apr 4, 2000
Appl. No.:
09/542314
Inventors:
Valentina Kon - Nashville TN
Agnes Fogo - Mount Juliet TN
Iekuni Ichikawa - Nashville TN
Agnes Fogo - Mount Juliet TN
Iekuni Ichikawa - Nashville TN
Assignee:
Vanderbilt University - Nashville TN
International Classification:
A61K 3144
US Classification:
514303, 574300
Abstract:
This invention provides a method of and compositions for increasing or maintaining glomerular filtration rate while preserving renal structure in a patient comprising administering an angiotensin II type 1 vascular receptor antagonist to the patient, independent of its effects on systemic blood pressure. The invention provides that, by administering the AII type 1 receptor antagonist, blood flow to the kidney can be improved without sacrificing intraglomerular pressure and therefore glomerular filtration and that even with this enhanced glomerular pressure and filtration, renal structure is preserved. Also provided is a method of screening AII type 1 receptor antagonists for the ability to maintain or increase glomerular filtration rate while decreasing mesangial matrix accumulation comprising the steps of administering the antagonist in an animal model characterized by decreased glomerular filtration rate and increased mesangial matrix accumulation and selecting the compounds that increase glomerular filtration rate while decreasing mesangial matrix accumulation.
Method And Compositions For Maintaining Glomerular Filtration Rate While Inhibiting Extracellular Matrix Accumulation
US Patent:
5512580, Apr 30, 1996
Filed:
Jul 25, 1994
Appl. No.:
8/279901
Inventors:
Valentina Kon - Nashville TN
Agnes Fogo - Mount Juliet TN
Iekuni Ichikawa - Nashville TN
Agnes Fogo - Mount Juliet TN
Iekuni Ichikawa - Nashville TN
Assignee:
Vanderbilt University - Nashville TN
International Classification:
A61K 3144
US Classification:
514303
Abstract:
This invention provides a method of and compositions for increasing or maintaining glomerular filtration rate while preserving renal structure in a patient comprising administering an angiotensin II type 1 vascular receptor antagonist to the patient, independent of its effects on systemic blood pressure. The invention provides that, by administering the AII type 1 receptor antagonist, blood flow to the kidney can be improved without sacrificing intraglomerular pressure and therefore glomerular filtration and that even with this enhanced glomerular pressure and filtration, renal structure is preserved. Also provided is a method of screening AII type 1 receptor antagonists for the ability to maintain or increase glomerular filtration rate while decreasing mesangial matrix accumulation comprising the steps of administering the antagonist in an animal model characterized by decreased glomerular filtration rate and increased mesangial matrix accumulation and selecting the compounds that increase glomerular filtration rate while decreasing mesangial matrix accumulation.
Method And Compositions For Maintaining Glomerular Filtration Rate While Inhibiting Extracellular Matrix Accumulation
US Patent:
5677312, Oct 14, 1997
Filed:
Jun 6, 1995
Appl. No.:
8/468242
Inventors:
Valentina Kon - Nashville TN
Agnes Fogo - Mount Juliet TN
Iekuni Ichikawa - Nashville TN
Agnes Fogo - Mount Juliet TN
Iekuni Ichikawa - Nashville TN
Assignee:
Vanderbilt University - Nashville TN
International Classification:
A61K 3144
US Classification:
514303
Abstract:
This invention provides a method of and compositions for increasing or maintaining glomerular filtration rate while preserving renal structure in a patient comprising administering an angiotensin II type 1 vascular receptor antagonist to the patient, independent of its effects on systemic blood pressure. The invention provides that, by administering an AII type 1 receptor antagonist, blood flow to the kidney can be improved without sacrificing intraglomerular pressure and therefore glomerular filtration and that even with this enhanced glomerular pressure and filtration, renal structure is preserved. Also provided is a method of screening AII type 1 receptor antagonists for the ability to maintain or increase glomerular filtration rate while decreasing mesangial matrix accumulation comprising the steps of administering the antagonist in an animal model characterized by decreased glomerular filtration rate and increased mesangial matrix accumulation and selecting the compounds that increase glomerular filtration rate while decreasing mesangial matrix accumulation.
Method Of Screening Of Angiotens In Ii Type I Receptor Antagonists
US Patent:
5660813, Aug 26, 1997
Filed:
Jun 6, 1995
Appl. No.:
8/467456
Inventors:
Valentina Kon - Nashville TN
Agnes Fogo - Mount Juliet TN
Iekuni Ichikawa - Nashville TN
Agnes Fogo - Mount Juliet TN
Iekuni Ichikawa - Nashville TN
Assignee:
Vanderbilt University - Nashville TN
International Classification:
A61K 4900
US Classification:
424 92
Abstract:
This invention provides a method of and compositions for increasing or maintaining glomerular filtration rate while preserving renal structure in a patient comprising administering an angiotensin II type 1 vascular receptor antagonist to the patient, independent of its effects on systemic blood pressure. The invention provides that, by administering an AII type 1 receptor antagonist, blood flow to the kidney can be improved without sacrificing intraglomerular pressure and therefore glomerular filtration and that even with this enhanced glomerular pressure and filtration, renal structure is preserved. Also provided is a method of screening AII type 1 receptor antagonists for the ability to maintain or increase glomerular filtration rate while decreasing mesangial matrix accumulation comprising the steps of administering the antagonist in an animal model characterized by decreased glomerular filtration rate and increased mesangial matrix accumulation and selecting the compounds that increase glomerular filtration rate while decreasing mesangial matrix accumulation.